CAS 25507-04-4

Clindamycin palmitate hydrochloride

Description:

Clindamycin palmitate hydrochloride is a semi-synthetic antibiotic derived from lincomycin, primarily used to treat various bacterial infections, particularly those caused by anaerobic bacteria and certain strains of streptococci. It is characterized by its white to off-white crystalline powder form, which is soluble in water and exhibits stability under normal storage conditions. The substance functions by inhibiting bacterial protein synthesis, thereby exerting its antimicrobial effects. Clindamycin palmitate hydrochloride is often administered in oral formulations, making it suitable for pediatric use due to its palmitate ester, which enhances its taste and palatability. The hydrochloride salt form improves its solubility and bioavailability. As with any antibiotic, it is essential to use clindamycin palmitate hydrochloride judiciously to prevent the development of antibiotic resistance. Potential side effects may include gastrointestinal disturbances and allergic reactions, necessitating careful monitoring during treatment. Overall, it is a valuable therapeutic agent in the management of specific infections, particularly in patients who are allergic to penicillin.

Formula: C₃₄H₆₃ClN₂O₆S·ClH

InChI: InChI=1S/C34H63ClN2O6S.ClH/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-21-27(38)42-32-30(40)29(39)31(43-34(32)44-5)28(24(3)35)36-33(41)26-22-25(20-7-2)23-37(26)4;/h24-26,28-32,34,39-40H,6-23H2,1-5H3,(H,36,41);1H/t24-,25+,26-,28+,29+,30-,31+,32+,34+;/m0./s1

InChI key: InChIKey=GTNDZRUWKHDICY-DJHAJVGHSA-N

SMILES: [C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)([C@H](C)Cl)[C@]2(O[C@H](SC)[C@H](OC(CCCCCCCCCCCCCCC)=O)[C@@H](O)[C@H]2O)[H].Cl

Synonyms:

• <span class="text-smallcaps">L</smallcap>-threo-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, 2-palmitate, monohydrochloride, trans-α-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride, (2S-trans)-
• <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride
• Cleocin Pediatric
• Clindamycin 2-palmitate hydrochloride
• Clindamycin palmitate hydrochloride
• Palmitic acid, 2-ester with methyl 7-chloro-6,7,8-trideoxy-6-(trans-1-methyl-4-propyl-<span class="text-smallcaps">L</smallcap>-2-pyrrolidinecarboxamido)-1-thio-<smallcap>L</smallcap>-threo-α-<smallcap>D</span>-galacto-octopyranoside monohydrochloride
• [(2R,3R,4S,5R,6R)-6-[2-chloro-1-[[(2S,4R)-1-methyl-4-propyl-pyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyl-tetrahydropyran-3-yl] hexadecanoate hydrochloride
• methyl 7-chloro-6,7,8-trideoxy-2-O-hexadecanoyl-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-alpha-D-galacto-octopyranoside hydrochloride (1:1)
• methyl 7-chloro-6,7,8-trideoxy-2-O-hexadecanoyl-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-beta-L-erythro-octopyranoside hydrochloride (1:1)
• L-threo-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, 2-palmitate, monohydrochloride, trans-α-
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride
• L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-hexadecanoate, monohydrochloride, (2S-trans)-

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Antibiotics nesoi

Formula: C₃₄H₆₃ClN₂O₆S·HCl

Color and Shape: White Off-White Powder

Molecular weight: 662.40954

Ref: 45-1137005

Clindamycin 2-Palmitate

CAS: 25507-04-4

Formula: C₃₄H₆₃ClN₂O₆S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 663.41 36.46

Ref: 4Z-C-5026

Clindamycin palmitate hydrochloride

CAS: 25507-04-4

Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is the hydrochloride salt of clindamycin and palmitate, a lincosamide antibiotic.

Formula: C₃₄H₆₃ClN₂O₆S·HCl

Purity: 98%

Color and Shape: Solid

Molecular weight: 699.85

Ref: TM-T6449

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Color and Shape: Neat

Ref: 61-FOR1989.00

Clindamycin Palmitate Hydrochloride

Controlled Product

CAS: 25507-04-4

Formula: C₃₄H₆₃ClN₂O₆S·ClH

Color and Shape: Neat

Molecular weight: 699.85

Ref: 86-MM1989.00

Clindamycin Palmitate Hydrochloride

Controlled Product

CAS: 25507-04-4

Applications Clindamycin Palmitate is a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial.
References Platzer, D., et al.: J. Pharm. Biomed. Anal., 41, 84 (2006),

Formula: C₃₄H₆₃ClN₂O₆S·ClH

Color and Shape: Neat

Molecular weight: 699.85

Ref: TR-C580035

Clindamycin Palmitate Hydrochloride

CAS: 25507-04-4

Formula: C₃₄H₆₃ClN₂O₆SHCl

Molecular weight: 663.4 : 36.5

Ref: ST-EA-CP-C26050