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CAS 25520-83-6

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3’-Fluoro-3’-deoxythymidine Monophosphate

Description:
3’-Fluoro-3’-deoxythymidine monophosphate (dFMP) is a nucleotide analog that serves as a building block for nucleic acids. It is characterized by the presence of a fluorine atom at the 3' position of the deoxythymidine structure, which replaces the hydroxyl group typically found in natural nucleotides. This modification imparts unique properties, such as increased resistance to enzymatic degradation and altered base-pairing characteristics, making it valuable in molecular biology and medicinal chemistry. dFMP is often utilized in the development of antiviral and anticancer therapies, as it can interfere with DNA synthesis and replication processes. The compound is typically soluble in aqueous solutions, and its stability can be influenced by pH and temperature. Additionally, its structural similarity to natural nucleotides allows it to be incorporated into DNA by polymerases, which can lead to the disruption of normal cellular functions. Overall, 3’-Fluoro-3’-deoxythymidine monophosphate is an important tool in research and therapeutic applications, particularly in the context of viral infections and cancer treatment.
Formula:C10H14FN2O7P
Synonyms:
  • 2’,3’-dideoxy-3’-fluoro-5-methyluridine 5’-(Dihydrogen Phosphate)
  • 3’-Deoxy-3’-fluorothymidine-5’-monophosphate
  • 3’-Deoxy-3’-fluoro-5’-thymidylic Acid
  • 3’-Deoxy-3’-fluorothymidine Monophosphate
  • 3’-Fluoro-3’-deoxythymidine Monophosphate
  • 5'-Thymidylic acid, 3'-deoxy-3'-fluoro-
  • 2',3'-dideoxy-3'-fluoro-5-methyluridine 5'-(Dihydrogen Phosphate)
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