CAS 25521-31-7

(3R,6R)-3,4,5-trihydroxy-6-[[11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-yl]oxy]tetrahydropyran-2-carboxylic acid

Description:

The chemical substance known as (3R,6R)-3,4,5-trihydroxy-6-[[11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-yl]oxy]tetrahydropyran-2-carboxylic acid, with the CAS number 25521-31-7, is characterized by its complex molecular structure that includes multiple functional groups. It features a tetrahydropyran ring, which contributes to its cyclic nature, and several hydroxyl (-OH) groups that enhance its polarity and potential for hydrogen bonding. The presence of a carboxylic acid group (-COOH) indicates acidic properties, while the methylamino group suggests basic characteristics. This compound is likely to exhibit significant biological activity due to its structural features, which may interact with various biological targets. Its intricate arrangement of atoms and functional groups may also influence its solubility, stability, and reactivity in different environments. Overall, this substance represents a unique combination of organic functionalities that could be of interest in medicinal chemistry and pharmacology.

Formula: C₂₄H₃₀N₂O₇

InChI: InChI=1/C24H30N2O7/c1-25-11-4-12-26-17-6-3-2-5-14(17)7-8-15-13-16(9-10-18(15)26)32-24-21(29)19(27)20(28)22(33-24)23(30)31/h2-3,5-6,9-10,13,19-22,24-25,27-29H,4,7-8,11-12H2,1H3,(H,30,31)/t19?,20-,21?,22?,24+/m1/s1

2-Hydroxy Desipramine Glucuronide

CAS: 25521-31-7

Formula: C₂₄H₂₀N₂O₇

Color and Shape: White To Off-White Solid

Molecular weight: 458.51

Ref: 4Z-D-023

2-Hydroxy desipramine glucuronide

CAS: 25521-31-7

Ref: 7W-GC4429

2-Hydroxy desipramine-d6 glucuronide

CAS: 25521-31-7

Formula: C₂₄H₂₄D₆N₂O₇

Molecular weight: 464.55

Ref: 4Z-D-024

2-Hydroxy Desipramine β-D-Glucuronide

Controlled Product

CAS: 25521-31-7

Applications A metabolite of Desipramine.
References Gram, L.F., et al.: Clin. Pharmacol. Therap., 17, 555 (1975), Hackett, A.M., et al.: Xenobiotica, 14, 491 (1984), Chiba, M., et al.: Biochem. Pharmacol., 39, 367 (1990),

Formula: C₂₄H₃₀N₂O₇

Color and Shape: Neat

Molecular weight: 458.50

Ref: TR-H936510

2-Hydroxydesipramine glucuronide

CAS: 25521-31-7

2-Hydroxydesipramine glucuronide is a metabolite of desipramine, which is a tricyclic antidepressant that inhibits the uptake of noradrenaline and 5-hydroxytryptamine. 2-Hydroxydesipramine glucuronide is formed by conjugation with glucuronic acid. It has been found in human urine and has been proposed as a biomarker for the clinical monitoring of patients taking desipramine. The pharmacological effects of 2-hydroxydesipramine glucuronide are similar to those of desipramine, but it is less potent and selective than its parent compound. This metabolite also has biliary excretion properties, which may be due to its small molecular size.

Formula: C₂₄H₃₀N₂O₇

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 458.51 g/mol

Ref: 3D-MH10000

2-Hydroxy Desipramine-d3 β-D-Glucuronide

Controlled Product

CAS: 25521-31-7

Formula: C₂₄D₃H₂₇N₂O₇

Color and Shape: Neat

Molecular weight: 461.523

Ref: TR-H936512

2-Hydroxydesipramine b-D-glucuronide sodium salt

CAS: 25521-31-7

2-Hydroxydesipramine b-D-glucuronide sodium salt is a glucuronide metabolite of desipramine. It has been shown to be an active form of desipramine in animals and humans, but the exact mechanism of this activity is unknown. 2-Hydroxydesipramine b-D-glucuronide sodium salt is excreted in the bile and may have a therapeutic effect on liver disease. The pharmacological effects of 2-hydroxydesipramine b-D-glucuronide sodium salt have been studied using various animal models and human studies. This drug has been shown to produce sedative effects and to affect the cardiovascular system. In addition, it has an effect on the central nervous system, including its ability to lower seizure threshold.
2-Hydroxydesipramine b-D-glucuronide sodium salt also inhibits the metabolism of other drugs by inhib

Formula: C₂₄H₃₀N₂O₇·Na

Purity: Min. 95%

Molecular weight: 481.49 g/mol

Ref: 3D-MH09755

2-Hydroxy Desipramine Glucuronide

CAS: 25521-31-7

Formula: C₂₄H₃₀N₂O₇

Molecular weight: 456.5

Ref: ST-EA-CP-D34003