CAS 25521-33-9

3-doxyl-17beta-hydroxy-5alpha-androstane

Description:

3-Doxyl-17beta-hydroxy-5alpha-androstane, identified by its CAS number 25521-33-9, is a steroid compound that features a hydroxyl group at the 17-beta position and a doxyl group, which is a nitroxide radical, at the 3-position of the androstane backbone. This compound is characterized by its unique structural features that combine the steroid framework with a stable free radical, which can influence its chemical reactivity and interactions. The presence of the hydroxyl group contributes to its potential solubility in polar solvents and may affect its biological activity, while the doxyl group can serve as a spin label in electron paramagnetic resonance (EPR) studies, allowing researchers to investigate molecular dynamics and interactions in various environments. Overall, 3-doxyl-17beta-hydroxy-5alpha-androstane is of interest in both biochemical research and potential applications in pharmacology, particularly in studies related to steroid behavior and radical chemistry.

Formula: C₂₃H₃₈NO₃

InChI: InChI=1/C23H38NO3/c1-20(2)14-27-23(24(20)26)12-11-21(3)15(13-23)5-6-16-17-7-8-19(25)22(17,4)10-9-18(16)21/h15-19,25H,5-14H2,1-4H3/t15-,16?,17?,18?,19-,21-,22-,23?/m0/s1

SMILES: CC1(C)COC2(CC[C@@]3(C)[C@@H](CCC4C5CC[C@@H]([C@@]5(C)CCC34)O)C2)N1O

Synonyms:

• 3-DOXYL-17beta-hydroxy-5alpha-androstane,free radical
• [(5S,10S,13S,17S)-17-hydroxy-4',4',10,13-tetramethylhexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-3,2'-[1,3]oxazolidin]-3'-yl]oxidanyl

Androstane Spin Label (ASL)

Controlled Product

CAS: 25521-33-9

Applications Androstane Spin Label (ASL) is a spin labelled Androstane used to mimic Androstane.
References Scheidt, H., et al.: J. Biol. Chem., 278, 45563 (2003);

Formula: C₂₃H₃₈NO₃

Color and Shape: Neat

Molecular weight: 376.55

Ref: TR-A637395

Androstane Spin Label (ASL)-d3

Controlled Product

CAS: 25521-33-9

Formula: C₂₃H₃₅D₃NO₃

Color and Shape: Neat

Molecular weight: 376.547

Ref: TR-A637397

Androstane Spin Label

CAS: 25521-33-9

Formula: C₂₃H₃₈NO₃

Molecular weight: 376.56

Ref: ST-EA-CP-P133163