CAS 255730-18-8: Artemisone

Description: Artemisone is a synthetic derivative of artemisinin, a compound originally derived from the sweet wormwood plant, Artemisia annua, known for its antimalarial properties. With the CAS number 255730-18-8, Artemisone exhibits a unique chemical structure that enhances its efficacy against malaria parasites, particularly in resistant strains. It is characterized by its ability to generate reactive oxygen species upon activation, which contributes to its antimalarial activity. Artemisone has shown promising results in preclinical studies, demonstrating a favorable pharmacokinetic profile, including good oral bioavailability and a relatively long half-life. Additionally, it has been investigated for its potential to treat other parasitic infections and may possess anti-inflammatory properties. The compound is typically studied in the context of drug development for malaria treatment, with ongoing research aimed at optimizing its therapeutic potential and minimizing side effects. As with any pharmaceutical agent, understanding its mechanism of action, safety profile, and efficacy in clinical settings is crucial for its application in medicine.

Formula: C₁₉H₃₁NO₆S

InChI: InChI=1S/C19H31NO6S/c1-12-4-5-15-13(2)16(20-8-10-27(21,22)11-9-20)23-17-19(15)14(12)6-7-18(3,24-17)25-26-19/h12-17H,4-11H2,1-3H3/t12-,13-,14+,15+,16-,17-,18-,19-/m1/s1

InChI key: InChIKey=FDMUNKXWYMSZIR-NQWKWHCYSA-N

SMILES: O=S1(=O)CCN(CC1)C2OC3OC4(OOC35C(CC4)C(C)CCC5C2C)C

Synonyms:

• 10a-[4'-(S,S-Dioxothiomorpholin-1'-yl)]-10-deoxodihydroartemisinin
• Artemifone
• Artemisone
• Bay 44-9585
• Thiomorpholine, 4-[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]-, 1,1-dioxide

Artemisone

CAS: 255730-18-8

Artemisone (BAY 44-9585) is a potent and semi-synthetic antimalarial, inhibits P.

• Formula: C₁₉H₃₁NO₆S
• Purity: 99.90%
• Color and Shape: Solid
• Molecular weight: 401.52

4-((3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-Trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)thiomorpholine 1,1-dioxide

CAS: 255730-18-8

• Formula: C₁₉H₃₁NO₆S
• Color and Shape: Neat
• Molecular weight: 401.517

4-((3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-Trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)thiomorpholine 1,1-dioxide-3,3,5,5-d4

CAS: 255730-18-8

• Formula: C₁₉H₃₁NO₆S
• Color and Shape: Neat
• Molecular weight: 405.5

Artemisone

CAS: 255730-18-8

Please enquire for more information about Artemisone including the price, delivery time and more detailed …

• Formula: C₁₉H₃₁NO₆S
• Purity: Min. 95%
• Molecular weight: 401.52 g/mol