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CAS 2559686-28-9

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  • KIM-161
    Targetmol
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    KIM-161

    CAS:
    <p>KIM-161 is a PIK3CA inhibitor. It demonstrates significant antiproliferative activity, with IC50 values of 1.428 and 1.562 µM against PI3KCA-mutant breast cancer cell lines MCF7 and T47D, respectively. KIM-161 induces apoptosis and cell cycle arrest by inhibiting the PI3K/AKT/mTOR signaling pathway, leading to ROS production. It is applicable for research on breast cancer and its PI3KCA-mutant subtypes.</p>
    Formula:C27H25N3O3
    Color and Shape:Solid
    Molecular weight:439.51

    Ref: TM-T207206