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CAS 2559738-69-9

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  • Mitapivat hydrochloride
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    Mitapivat hydrochloride

    CAS:
    <p>Mitapivat (AG-348) hydrochloride is an orally active and selective allosteric activator of pyruvate kinase R (PK-R). It enhances the PK-R-catalyzed conversion of phosphoenolpyruvate to pyruvate, thereby promoting the glycolysis pathway, increasing ATP production in red blood cells, and decreasing 2,3-diphosphoglycerate (2,3-DPG) levels. Mitapivat hydrochloride is being investigated for potential use in the study of pyruvate kinase deficiency and other anemia-related disorders.</p>
    Formula:C24H27ClN4O3S
    Color and Shape:Solid
    Molecular weight:487.014

    Ref: TM-T206172