SGC-CAMKK2-1, with the CAS number 2561494-76-4, is a small molecule inhibitor specifically targeting the calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2). This compound is part of a broader class of kinase inhibitors that modulate cellular signaling pathways, particularly those involved in metabolic regulation and energy homeostasis. SGC-CAMKK2-1 is characterized by its ability to selectively inhibit CAMKK2 activity, which plays a crucial role in various physiological processes, including glucose metabolism and neuronal function. The compound is typically evaluated for its efficacy in biochemical assays and cellular models to understand its potential therapeutic applications, particularly in metabolic disorders and neurodegenerative diseases. Its chemical structure and properties, such as solubility and stability, are essential for its bioavailability and effectiveness in biological systems. As research continues, SGC-CAMKK2-1 may provide insights into the modulation of CAMKK2-related pathways and contribute to the development of novel therapeutic strategies.

SGC-CAMKK2-1

2561494-76-4: SGC-CAMKK2-1, with the CAS number 2561494-76-4, is a small molecule inhibitor specifically targeting the calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2). This compound is part of a broader class of kinase inhibitors that modulate cellular signaling pathways, particularly those involved in metabolic regulation and energy homeostasis. SGC-CAMKK2-1 is characterized by its ability to selectively inhibit CAMKK2 activity, which plays a crucial role in various physiological processes, including glucose metabolism and neuronal function. The compound is typically evaluated for its efficacy in biochemical assays and cellular models to understand its potential therapeutic applications, particularly in metabolic disorders and neurodegenerative diseases. Its chemical structure and properties, such as solubility and stability, are essential for its bioavailability and effectiveness in biological systems. As research continues, SGC-CAMKK2-1 may provide insights into the modulation of CAMKK2-related pathways and contribute to the development of novel therapeutic strategies.

SGC-CAMKK2-1 is a selective inhibitor of calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC50 of 30 nM. It effectively inhibits AMPK phosphorylation in C4-2 cells, exhibiting an IC50 value of 1.6 µM.

CAS 2561494-76-4

SGC-CAMKK2-1

SGC-CAMKK2-1

Ref: TM-T205037