CAS 25627-36-5

1-Propanamine, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride, (E)-

Description:

1-Propanamine, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride, with the CAS number 25627-36-5, is a chemical compound that belongs to the class of amines and is characterized by its complex structure, which includes a thiepin ring fused with two benzene rings. This compound typically exhibits properties associated with both amines and aromatic systems, such as potential basicity due to the presence of the amine group. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, enhancing its bioavailability in pharmaceutical applications. The (E)-configuration indicates a specific geometric arrangement around the double bond, which can influence its biological activity and interaction with receptors. This compound may be of interest in medicinal chemistry, particularly in the development of psychoactive or therapeutic agents, given its structural features that resemble known pharmacophores. However, detailed studies on its pharmacodynamics, toxicity, and specific applications would be necessary to fully understand its characteristics and potential uses.

Formula: C₁₉H₂₁NS·ClH

InChI: InChI=1S/C19H21NS.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11+;

InChI key: InChIKey=XUPZAARQDNSRJB-SJDTYFKWSA-N

SMILES: C(\CCN(C)C)=C/1\C=2C(CSC=3C1=CC=CC3)=CC=CC2.Cl

Synonyms:

• Dibenzo[b,e]thiepin-D11(6H),g-propylamine, N,N-dimethyl-, hydrochloride,(E)- (8CI)
• Dibenzo[b,e]thiepin, 1-propanamine deriv.
• Dibenzo[b,e]thiepin-Δ11(6H),γ-propylamine, N,N-dimethyl-, hydrochloride, (E)-
• 1-Propanamine, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride, (E)-
• Dibenzo[b,e]thiepin, 1-propanamine deriv.

Dothiepin HCl

CAS: 25627-36-5

Dothiepin HCl: TCA, SNRI, with antihistamine, antiadrenergic, anticholinergic, and sodium block properties.

Formula: C₁₉H₂₂ClNS

Color and Shape: Solid

Molecular weight: 331.9

Ref: TM-T69579