CAS 256376-24-6

5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine

Description:

5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine, with CAS number 256376-24-6, is a chemical compound characterized by its complex structure, which includes a cyclopropyl group, a pyrazolo-pyridine moiety, and a pyrimidinamine component. This compound is typically classified as a small organic molecule and may exhibit biological activity, potentially serving as a pharmacological agent. Its structure suggests the presence of multiple functional groups, which can influence its solubility, stability, and reactivity. The fluorophenyl substitution may enhance its lipophilicity and affect its interaction with biological targets. The compound's synthesis and characterization would involve standard organic chemistry techniques, including purification methods such as chromatography. Additionally, its potential applications could be explored in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways. As with many compounds of this nature, understanding its properties would require further investigation into its physical and chemical characteristics, as well as its biological effects.

Formula: C₂₀H₁₇FN₆

InChI: InChI=1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25)

InChI key: InChIKey=ATOAHNRJAXSBOR-UHFFFAOYSA-N

SMILES: C(N1N=C(C=2C1=NC=CC2)C=3N=C(N)C(=CN3)C4CC4)C5=C(F)C=CC=C5

Synonyms:

• 4-Pyrimidinamine, 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-
• 5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine
• Bay-41-2272

BAY 41-2272

CAS: 256376-24-6

Formula: C₂₀H₁₇FN₆

Purity: 99%

Color and Shape: Solid

Molecular weight: 360.3876

Ref: IN-DA007MGP

BAY 41-2272

CAS: 256376-24-6

BAY 41-2272

Purity: ≥98%

Molecular weight: 360.39g/mol

Ref: 54-BUP09895

BAY 41-2272

CAS: 256376-24-6

BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator.

Formula: C₂₀H₁₇FN₆

Purity: 99.54%

Color and Shape: Solid

Molecular weight: 360.39

Ref: TM-T6775

5-Cyclopropyl-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-amine

CAS: 256376-24-6

Purity: 95.0%

Molecular weight: 360.39599609375

Ref: 10-F497507

BAY 41-2272

Controlled Product

CAS: 256376-24-6

Applications BAY 41-2272 is a soluble guanylate cyclase agonist that activates human mononuclear phagocytes. Inhibits vascular smooth muscle growth through the cAMP-dependent protein kinase and cGMP-dependent protein kinase pathways.
References Soeiro-Pereira, P. et al.: British. J. Pharmacol., 166, 1617 (2012); Joshi, C. et al.: J. Pharmacol. Exp. Ther., 339, 394 (2011)

Formula: C₂₀H₁₇FN₆

Color and Shape: Neat

Molecular weight: 360.39

Ref: TR-B118920

BAY 41-2272

CAS: 256376-24-6

BAY 41-2272 is a cyclase inhibitor that blocks the production of cyclic adenosine monophosphate (cAMP). It has been shown to inhibit the activity of the α1 subunit of phosphodiesterase, which is involved in the production of cAMP. BAY 41-2272 has been shown to have pharmacological effects in vitro, such as inhibiting cell proliferation, and physiological effects, such as decreasing blood pressure. BAY 41-2272 also inhibits signal pathways in mammalian cells, such as protein kinase A (PKA) and mitogen-activated protein kinases (MAPKs).

Formula: C₂₀H₁₇FN₆

Purity: Min. 95%

Molecular weight: 360.39 g/mol

Ref: 3D-GKA37624