CAS 256376-62-2

1H-Pyrazolo[3,4-b]pyridine-3-carboxamide, 1-[(2-fluorophenyl)methyl]-

Description:

1H-Pyrazolo[3,4-b]pyridine-3-carboxamide, 1-[(2-fluorophenyl)methyl]- is a chemical compound characterized by its pyrazolo-pyridine core structure, which is a bicyclic compound featuring both pyrazole and pyridine rings. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity due to the presence of the carboxamide functional group, which can participate in hydrogen bonding and influence its interaction with biological targets. The presence of the 2-fluorophenyl group may enhance its lipophilicity and alter its pharmacokinetic properties. This compound is of interest in medicinal chemistry, particularly for its potential applications in drug development, as derivatives of pyrazolo-pyridine structures have been explored for various therapeutic effects, including anti-inflammatory and anti-cancer activities. Its molecular structure and functional groups suggest that it may engage in specific interactions with biological macromolecules, making it a candidate for further research in pharmacology and medicinal chemistry.

Formula: C₁₄H₁₁FN₄O

InChI: InChI=1S/C14H11FN4O/c15-11-6-2-1-4-9(11)8-19-14-10(5-3-7-17-14)12(18-19)13(16)20/h1-7H,8H2,(H2,16,20)

InChI key: InChIKey=GWDSAMDSGSEPRH-UHFFFAOYSA-N

SMILES: C(N1C=2C(C(C(N)=O)=N1)=CC=CN2)C3=C(F)C=CC=C3

Synonyms:

• 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide
• 1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboxamide
• 1-[(2-Fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carboxamide
• 1H-Pyrazolo[3,4-b]pyridine-3-carboxamide, 1-[(2-fluorophenyl)methyl]-
• 1-(2-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide hydrochloride
• Riociguat-19
• Riociguat Impurity 2/1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

Riociguat Impurity 37

CAS: 256376-62-2

Formula: C₁₄H₁₁FN₄O

Molecular weight: 270.27

Ref: ST-EA-CP-R35045