CAS 2564-35-4

dGTP

Description:

dGTP, or deoxyguanosine triphosphate, is a nucleotide that plays a crucial role in cellular metabolism and DNA synthesis. It is composed of a deoxyribose sugar, a guanine base, and three phosphate groups. As a building block of DNA, dGTP is essential for the polymerization process during DNA replication and repair. The presence of the deoxyribose sugar distinguishes it from its ribonucleotide counterpart, GTP, which contains ribose. dGTP is involved in various biochemical pathways, including energy transfer and signaling, due to its high-energy phosphate bonds. It is also a substrate for DNA polymerases, which catalyze the addition of nucleotides to a growing DNA strand. The CAS number 2564-35-4 uniquely identifies this compound in chemical databases, facilitating its study and application in research and biotechnology. Overall, dGTP is vital for genetic information storage and transmission, making it a key player in molecular biology.

Formula: C₁₀H₁₆N₅O₁₃P₃

InChI: InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1

InChI key: InChIKey=HAAZLUGHYHWQIW-KVQBGUIXSA-N

SMILES: O=C1C2=C(N(C=N2)[C@@H]3O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)C3)NC(N)=N1

Synonyms:

• 2'-Deoxy-5'-GTP
• 2'-Deoxyguanosine 5'-triphosphate
• 2'-Desoxyguanosin-5'-(tetrahydrogentriphosphat)
• 2-amino-9-[2-deoxy-5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)pentofuranosyl]-3,9-dihydro-6H-purin-6-one
• 5'-(Tetrahidrogenotrifosfato) De 2'-Desoxiguanosina
• 5'-(Tetrahydrogenotriphosphate) De 2'-Desoxyguanosine
• 5'-Dgtp
• Deoxy-GTP
• Deoxyguanosine 5'-triphosphate
• Deoxyguanosine triphosphate
• Guanosine 2'-deoxy-, 5'-triphosphate
• Guanosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-
• Guanosine 5'-(tetrahydrogen triphosphate), 2'-deoxy- (9CI)
• Guanosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate)
• dGTP
• 2′-Deoxyguanosine 5′-(tetrahydrogen triphosphate)

dGTP

CAS: 2564-35-4

dGTP

Purity: ≥98%

Molecular weight: 507.18g/mol

Ref: 54-BUP05209

dGTP

CAS: 2564-35-4

dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and

Formula: C₁₀H₁₆N₅O₁₃P₃

Purity: 99.64%

Color and Shape: Solid

Molecular weight: 507.18

Ref: TM-T40192

2'-Deoxyguanosine 5'-triphosphate Trisodium Salt

CAS: 2564-35-4

Formula: C₁₀H₁₃N₅O₁₃P₃·3Na

Molecular weight: 504.16 3 22.99

Ref: 4Z-G-2419

2’-Deoxyguanosine 13C5 5’-Triphosphate Triethylamine Salt

Controlled Product

CAS: 2564-35-4

Formula: C₅C₅H₁₆N₅O₁₃P₃•x(C₆H₁₅N)

Color and Shape: Neat

Molecular weight: 512.14 + x(101.19)

Ref: TR-G839000

2'-Deoxyguanosine-5'-triphosphate sodium salt - 100mmol solution

CAS: 2564-35-4

2'-Deoxyguanosine-5'-triphosphate sodium salt is a triphosphate with antiviral and antifungal activity. It has been shown to inhibit the proliferation of HL60 cells and induce apoptosis in IL-2 receptor-bearing cells. The compound inhibits the growth of opportunistic fungi, such as Aspergillus niger and Candida albicans, by binding to deoxyguanosine residues in DNA. The compound also blocks polymerase activity, preventing DNA replication. 2'-Deoxyguanosine-5'-triphosphate sodium salt is used as a model system for studying the binding of nucleoside analogs to DNA. This drug is prepared as an injection solution for intravenous administration.

Formula: C₁₀H₁₆N₅O₁₃P₃

Purity: Min. 95%

Molecular weight: 507.18 g/mol

Ref: 3D-ND46292

L-Adenosine 5'-triphosphate sodium salt

CAS: 2564-35-4

L-Adenosine 5'-triphosphate sodium salt is a monophosphate, diphosphate, and triphosphate analog of adenosine that is used as an antiviral agent. L-Adenosine 5'-triphosphate sodium salt is a synthetic nucleoside that is modified at the ribose sugar to form a phosphoramidite. This modification increases the stability of the molecule and prevents hydrolysis by ribonucleases. L-Adenosine 5'-triphosphate sodium salt is also known as Ado-5'-P or ATPγS.

Formula: C₁₀H₁₂N₅O₁₃P₃Na₄

Purity: Min. 95%

Molecular weight: 595.11 g/mol

Ref: 3D-NA63217