CAS 256411-32-2

Camtobell

Description:

Camtobell, with the CAS number 256411-32-2, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential applications in cancer treatment. It is classified as a small molecule and is known for its ability to interact with specific biological targets, which may contribute to its therapeutic effects. The compound typically exhibits properties such as moderate solubility in organic solvents and may have a complex structure that includes various functional groups, influencing its reactivity and biological activity. Camtobell's mechanism of action often involves the modulation of cellular pathways, making it a subject of interest in drug development. As with many compounds in this category, its efficacy and safety profile are evaluated through preclinical and clinical studies to determine its potential as a therapeutic agent. Further research is essential to fully understand its characteristics, including pharmacokinetics, pharmacodynamics, and potential side effects.

Formula: C₂₅H₂₇N₃O₄

InChI: InChI=1/C25H27N3O4/c1-4-25(31)19-11-21-22-17(12-28(21)23(29)18(19)13-32-24(25)30)15(9-10-26-14(2)3)16-7-5-6-8-20(16)27-22/h5-8,11,14,26,31H,4,9-10,12-13H2,1-3H3/t25-/m0/s1

InChI key: InChIKey=LNHWXBUNXOXMRL-VWLOTQADSA-N

SMILES: O=C1N2C(C=3C(C2)=C(CCNC(C)C)C=4C(N3)=CC=CC4)=CC5=C1COC(=O)[C@@]5(CC)O

Synonyms:

• (4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• (4S)-4-ethyl-4-hydroxy-11-{2-[(1-methylethyl)amino]ethyl}-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• (S)-4-Ethyl-4-hydroxy-11-[2-(isopropylamino)ethyl]-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione
• 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-, (4S)-
• 7-[2-(N-Isopropylamino)ethyl]-(20S)-camptothecin
• Belotecan
• Camtobell
• CKD-602
• BELOTECAN; CKD 602; CKD-602
• LNHWXBUNXOXMRL-VWLOTQADSA-N
• CKD602/CAMTOBELL

Belotecan

CAS: 256411-32-2

Belotecan is a drug that inhibits the angiogenic process by binding to the tetrazolium dye in vivo. Belotecan is administered intravenously and is used in combination therapy for solid tumours. It has been shown to inhibit tumor growth and metastasis in vivo models. Belotecan binds to monosodium salt which inhibits the ability of cancer cells to express P-glycoprotein (P-gp) substrate, thereby increasing the uptake of cytostatic drugs. This drug has also been shown to have inhibitory properties against infectious diseases such as tuberculosis, although it has not yet been approved for this use.

Formula: C₂₅H₂₇N₃O₄

Purity: Min. 95%

Molecular weight: 433.5 g/mol

Ref: 3D-GKA41132

Belotecan

CAS: 256411-32-2

Belotecan (CKD-602) inhibits DNA topoisomerase I, blocks cell cycle, induces apoptosis, and is a camptothecin-derived anticancer agent.

Formula: C₂₅H₂₇N₃O₄

Color and Shape: Solid

Molecular weight: 433.5

Ref: TM-T62435