CAS 2565637-94-5

N-(5-((4-Chlorobenzyl)oxy)-1,3,4-thiadiazol-2-yl)-4-(2-methoxyphenyl)nicotinamide

CAS: 2565637-94-5

N-(5-((4-Chlorobenzyl)oxy)-1,3,4-thiadiazol-2-yl)-4-(2-methoxyphenyl)nicotinamide

Purity: 98%

Molecular weight: 452.92g/mol

Ref: 54-OR1073964

AB25583

CAS: 2565637-94-5

AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.

Formula: C₂₂H₁₇ClN₄O₃S

Color and Shape: Solid

Molecular weight: 452.91

Ref: TM-T200101