CAS 2565705-03-3

Benzenesulfonamide, 3-[(4-amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-[[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino]-

Description:

Benzenesulfonamide, 3-[(4-amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-[[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino]- is a complex organic compound characterized by its sulfonamide functional group, which is known for its antibacterial properties. This compound features a triazine ring, which contributes to its potential biological activity, and a benzodioxole moiety that may enhance its pharmacological profile. The presence of chlorine and difluoro groups suggests that it may exhibit unique electronic properties and increased lipophilicity, potentially influencing its solubility and permeability. The stereochemistry indicated by the (S) configuration may also play a crucial role in its interaction with biological targets. Overall, this compound is likely to be of interest in medicinal chemistry, particularly in the development of new therapeutic agents, due to its multifaceted structure and potential for diverse biological activities. Further studies would be necessary to elucidate its specific mechanisms of action and therapeutic applications.

Formula: C₂₃H₁₉ClF₂N₈O₅S

Synonyms:

• Benzenesulfonamide, 3-[(4-amino-6-methoxy-1,3,5-triazin-2-yl)amino]-4-[[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]amino]-
• Dot1L-IN-5

Dot1L-IN-5

CAS: 2565705-03-3

Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein ( DOT1L ) with an IC 50 SPA DOT1L of 0.17 nM [1].

Formula: C₂₃H₁₉ClF₂N₈O₅S

Color and Shape: Solid

Molecular weight: 592.96

Ref: TM-T11084