CAS 2566-19-0

N-cbz-gly-gly

Description:

N-Cbz-gly-gly, also known as N-carbobenzyloxyglycylglycine, is a dipeptide derivative characterized by the presence of a carbobenzyloxy (Cbz) protecting group on the amino group of the first glycine residue. This compound is typically used in peptide synthesis and as an intermediate in the preparation of more complex peptides. Its structure consists of two glycine units linked by a peptide bond, with the Cbz group providing stability and protecting the amino functionality from unwanted reactions during synthesis. N-Cbz-gly-gly is generally soluble in polar organic solvents, and its properties can be influenced by the presence of the Cbz group, which enhances lipophilicity compared to unprotected glycine. The compound is often utilized in research and pharmaceutical applications, particularly in the development of peptide-based drugs and in studies involving peptide interactions. As with many peptide derivatives, it is important to handle N-Cbz-gly-gly with care, following appropriate safety protocols due to potential reactivity and biological activity.

Formula: C₁₂H₁₄N₂O₅

InChI: InChI=1/C12H14N2O5/c15-10(13-7-11(16)17)6-14-12(18)19-8-9-4-2-1-3-5-9/h1-5H,6-8H2,(H,13,15)(H,14,18)(H,16,17)

SMILES: c1ccc(cc1)COC(=NCC(=NCC(=O)O)O)O

Synonyms:

• Z-Gly-Gly-OH
• N-CBZ-Glycylglycine N-Carbobenzyloxy-glycylglycine
• N-[(benzyloxy)carbonyl]glycylglycine
• Cbz-Gly-Gly
• Cbz-Glycine-Glycine
• Cbz-Gly-Gly-OH

(Carbobenzoxy)glycylglycine

CAS: 2566-19-0

Formula: C₁₂H₁₄N₂O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 266.25

Ref: 3B-C2833

Z-Gly-Gly-OH

CAS: 2566-19-0

Bachem ID: 4000488.

Formula: C₁₂H₁₄N₂O₅

Purity: 97.3%

Color and Shape: White

Molecular weight: 266.25

Ref: 01-4000488

Glycine, N-[N-[(phenylmethoxy)carbonyl]glycyl]-

CAS: 2566-19-0

Formula: C₁₂H₁₄N₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 266.2500

Ref: IN-DA00I4WI

(N-Cbz-glycyl)glycine

CAS: 2566-19-0

(N-Cbz-glycyl)glycine

Purity: 99%

Molecular weight: 266.25g/mol

Ref: 54-OR1008381

N-[(Benzyloxy)carbonyl]glycylglycine

CAS: 2566-19-0

Applications N-[(Benzyloxy)carbonyl]glycylglycine is a reagent in the synthesis of Glycylglycyl-L-tyrosine (G718500), which is a fungal tyrosinases and their capability to oxidize peptide-bound tyrosine residues is important in a view of applicability of tyrosinases.
References Bowness, J., et al.: Biochem. J., 53, 620 (1953), Cuff, M., et al.: J. Mol. Biol., 278, 855 (1998), Kubo, I., et al.: Bioorg. Med. Chem., 12, 5349 (2004),

Formula: C₁₂H₁₄N₂O₅

Color and Shape: Neat

Molecular weight: 266.25

Ref: TR-B287100

2-(2-(((Benzyloxy)carbonyl)amino)acetamido)acetic acid

CAS: 2566-19-0

Formula: C₁₂H₁₄N₂O₅

Purity: 95%

Color and Shape: Solid, White to off-white powder

Molecular weight: 266.253

Ref: 10-F239066