Casein kinase 1δ-IN-31 is a small molecule inhibitor specifically targeting casein kinase 1 delta (CK1δ), an enzyme involved in various cellular processes, including circadian rhythm regulation, Wnt signaling, and cell proliferation. This compound is characterized by its ability to selectively inhibit CK1δ, which may have implications in therapeutic strategies for diseases such as cancer and neurodegenerative disorders. The molecular structure of Casein kinase 1δ-IN-31 typically includes functional groups that enhance its binding affinity to the enzyme's active site, promoting its inhibitory action. As a research tool, it is often utilized in biochemical assays to elucidate the role of CK1δ in cellular signaling pathways. The compound's pharmacokinetic properties, such as solubility, stability, and bioavailability, are crucial for its potential application in drug development. Overall, Casein kinase 1δ-IN-31 represents a valuable asset in the study of CK1δ-related biological processes and the development of targeted therapies.

Casein kinase 1δ-IN-31

2567490-30-4: Casein kinase 1δ-IN-31 is a small molecule inhibitor specifically targeting casein kinase 1 delta (CK1δ), an enzyme involved in various cellular processes, including circadian rhythm regulation, Wnt signaling, and cell proliferation. This compound is characterized by its ability to selectively inhibit CK1δ, which may have implications in therapeutic strategies for diseases such as cancer and neurodegenerative disorders. The molecular structure of Casein kinase 1δ-IN-31 typically includes functional groups that enhance its binding affinity to the enzyme's active site, promoting its inhibitory action. As a research tool, it is often utilized in biochemical assays to elucidate the role of CK1δ in cellular signaling pathways. The compound's pharmacokinetic properties, such as solubility, stability, and bioavailability, are crucial for its potential application in drug development. Overall, Casein kinase 1δ-IN-31 represents a valuable asset in the study of CK1δ-related biological processes and the development of targeted therapies.

<p>Casein kinase1δ-IN-31 (Compound 16) is an inhibitor of casein kinase (CK), specifically targeting CK1α, CK1δ, and p38α, with IC50 values of 196 nM, 17 nM, and 18 nM, respectively. Additionally, Casein kinase1δ-IN-31 inhibits Double Homeobox 4 (DUX4) with an IC50 of 1200 nM.</p>

CAS 2567490-30-4

Casein kinase 1δ-IN-31

Casein kinase 1δ-IN-31

Ref: TM-T205233