CAS 25679-24-7

cholecystokinin fragment 26-33 amide*non-sulfated

Description:

Cholecystokinin fragment 26-33 amide, non-sulfated, is a peptide derived from the larger cholecystokinin (CCK) molecule, which plays a crucial role in digestion and appetite regulation. This specific fragment consists of a sequence of amino acids that are involved in stimulating gallbladder contraction and promoting the release of digestive enzymes from the pancreas. The non-sulfated form indicates that it lacks sulfate modifications, which can influence its biological activity and receptor interactions. The CAS number 25679-24-7 uniquely identifies this compound in chemical databases, facilitating its study and application in research. Characteristically, this peptide is soluble in water and exhibits biological activity at nanomolar concentrations, making it significant in physiological processes. Its role in the gastrointestinal system and potential implications in appetite regulation and satiety make it a subject of interest in both pharmacological and nutritional research. Understanding its structure and function can provide insights into therapeutic approaches for digestive disorders and obesity management.

Formula: C₄₉H₆₂N₁₀O₁₃S₂

InChI: InChI=1/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)

SMILES: CSCCC(C(=NCC(=NC(Cc1c[nH]c2ccccc12)C(=NC(CCSC)C(=NC(CC(=O)O)C(=NC(Cc1ccccc1)C(=N)O)O)O)O)O)O)N=C(C(Cc1ccc(cc1)O)N=C(C(CC(=O)O)N)O)O

Synonyms:

• Cholecystokinin Octapeptide (desulfated)
• H-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
• N-[(2S)-2-hydrazino-3-phenylpropanoyl]-L-alpha-aspartyl-L-methionyl-L-tryptophylglycyl-N-[(1S,4S)-4-amino-5-carboxy-1-(4-hydroxybenzyl)-2,3-dioxopentyl]-L-methioninamide
• Alpha-Aspartyltyrosylmethionylglycyltryptophylmethionyl-Alpha-Aspartylphenylalaninamide

Cholecystokinin Octapeptide (desulfated)

CAS: 25679-24-7

Bachem ID: 4003323.

Formula: C₄₉H₆₂N₁₀O₁₃S₂

Purity: 98.1%

Color and Shape: White Lyophilisate

Molecular weight: 1063.22

Ref: 01-4003323

Cholecystokinin Octapeptide, desulfated

CAS: 25679-24-7

Cholecystokinin Octapeptide, desulfated

Purity: ≥95%

Molecular weight: 1063.21g/mol

Ref: 54-BUP21237

Cholecystokinin Octapeptide, desulfated

CAS: 25679-24-7

Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, non-sulfated) is an octapeptide composed of 8 amino acids from cholecystokinin-8.

Formula: C₄₉H₆₂N₁₀O₁₃S₂

Purity: 97.12%

Color and Shape: Solid

Molecular weight: 1063.21

Ref: TM-TP2204

CCK octapeptide Cholecystokinin (26-33)

CAS: 25679-24-7

The octapeptide cholecystokinin (26-33), known as CCK-8, has the full biological activity of the full-length cholecystokinin (CCK). CCK acts as a hormone and neurotransmitter and is found in the GI and central nervous systems. CCK-8 is a satiety peptide that inhibits food intake.CCK-8 can also inhibit amanitin uptake into hepatocytes.

Formula: C₄₉H₆₂N₁₀O₁₃S₂

Molecular weight: 1,063.21 g/mol

Ref: 3D-CRB1000237

CCK-Octapeptide (26-33) (Non-Sulfated Form)

CAS: 25679-24-7

CCK-Octapeptide (26-33) is a peptide that is a member of the cholecystokinin family of peptides. CCK-Octapeptide (26-33) is an activator of the CCK receptor and can be used for research purposes. This peptide has been shown to inhibit ion channels, which are proteins that regulate the flow of ions across cell membranes, and may be used as a pharmacological tool or research tool.

Formula: C₄₉H₆₂N₁₀O₁₃S₂

Purity: Min. 95%

Molecular weight: 1,063.2 g/mol

Ref: 3D-PCK-4087-V

Cholecystokinin Octapeptide (desulfated)

CAS: 25679-24-7

Cholecystokinin octapeptide (CCK-8) is a peptide hormone that is secreted from the pancreas. It is a conjugate of CCK and desulfated cholinesterase, which has been shown to have surfactant properties. The concentration-response curves for CCK-8 are biphasic, with an initial increase in contractility followed by a decrease. This response is caused by activation of both the B2 and B1 receptors in the paraventricular nucleus of the hypothalamus and subsequently release of pancreatic enzymes into the bloodstream. CCK-8 has also been shown to stimulate protein synthesis in gland cells such as those found in the pancreas.

Formula: C₄₉H₆₂N₁₀O₁₃S₂

Purity: Min. 95%

Molecular weight: 1,063.21 g/mol

Ref: 3D-FC108598