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CAS 2568273-82-3

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  • PROTAC SMARCA2/4-degrader-29
    Targetmol
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    PROTAC SMARCA2/4-degrader-29

    CAS:
    PROTAC SMARCA2/4-degrader-29 (Compound I-279) serves as a degrader for the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. In A549 cells, this compound effectively degrades SMARCA2 with a DC50 value of less than 100 nM, and similarly degrades SMARCA4 in MV411 cells with a DC50 under 100 nM.
    Formula:C44H51N11O4
    Color and Shape:Solid
    Molecular weight:797.95

    Ref: TM-T200058