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CAS 2568276-44-6

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  • PROTAC SMARCA2/4-degrader-30
    Targetmol
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    PROTAC SMARCA2/4-degrader-30

    CAS:
    Compound I-291, also known as PROTAC SMARCA2/4-degrader-30, targets the catalytic subunits of the SWI/SNF complex, specifically SMARCA2 and SMARCA4. It effectively degrades SMARCA2 in A549 and MV411 cells, as well as SMARCA4 in MV411 cells, with a degradation concentration (DC50) of less than 100 nM.
    Formula:C44H51N11O4
    Color and Shape:Solid
    Molecular weight:797.95

    Ref: TM-T200023