CAS 256952-63-3

WT1 126-134 peptide

CAS: 256952-63-3

WT1 126-134 peptide is a WT1 polypeptide (Wilms' tumor 1 peptide) (RMFPNAPYL) that activates cytotoxic CD8 T cells to target and destroy WT1+ tumor cells. It can form stable complexes with either H-2Db (murine) or HLA-A0201 (human) molecules. The WT1 126-134 peptide/HLA-A0201 complex exhibits high affinity for humanized monoclonal antibodies (IgG1), with a dissociation constant (Kd) of 0.2 nM. This peptide can be utilized as a T cell vaccine or an antibody target.

Formula: C₅₂H₇₇N₁₃O₁₂S

Color and Shape: Solid

Molecular weight: 1108.31

Ref: TM-TP3882