CAS 2577-52-8

4-[(Dipropylamino)sulfonyl]-2-nitrobenzoic acid

Description:

4-[(Dipropylamino)sulfonyl]-2-nitrobenzoic acid, with the CAS number 2577-52-8, is a chemical compound characterized by its sulfonamide functional group and a nitro group attached to a benzoic acid structure. This compound typically exhibits properties associated with both acidic and basic functionalities due to the carboxylic acid group and the dipropylamino moiety. It is generally soluble in polar organic solvents and may have limited solubility in water, depending on the pH. The presence of the nitro group contributes to its electron-withdrawing characteristics, which can influence its reactivity and interactions in various chemical environments. This compound is often utilized in pharmaceutical research and development, particularly in the synthesis of biologically active molecules. Its specific applications may include serving as an intermediate in drug synthesis or as a reagent in organic chemistry. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper laboratory practices.

Formula: C₁₃H₁₈N₂O₆S

InChI: InChI=1S/C13H18N2O6S/c1-3-7-14(8-4-2)22(20,21)10-5-6-11(13(16)17)12(9-10)15(18)19/h5-6,9H,3-4,7-8H2,1-2H3,(H,16,17)

InChI key: InChIKey=QVUYRWCZUQUOMI-UHFFFAOYSA-N

SMILES: S(N(CCC)CCC)(=O)(=O)C1=CC(N(=O)=O)=C(C(O)=O)C=C1

Synonyms:

• 2-Nitroprobenecid
• Benzoic acid, 4-[(dipropylamino)sulfonyl]-2-nitro-
• Benzoic acid, 4-(dipropylsulfamoyl)-2-nitro-
• 4-[(Dipropylamino)sulfonyl]-2-nitrobenzoic acid

2-Nitroprobenecid

Controlled Product

CAS: 2577-52-8

Applications 2-Nitroprobenecidis an analog of Probenecid (P755000), a uricosuric agent. It’s renal clearance is greater than that of 2-hydroxy or 2-chloroprobenecid.
References Blanchard, K.C. et al.: J. Pharmacol. Exp. Ther., 180. 397 (1972);

Formula: C₁₃H₁₈N₂O₆S

Color and Shape: Neat

Molecular weight: 330.36

Ref: TR-N518500

2-Nitroprobenecid-d14

Controlled Product

CAS: 2577-52-8

Formula: C₁₃D₁₄H₄N₂O₆S

Color and Shape: Neat

Molecular weight: 344.443

Ref: TR-N518502