CAS 257883-22-0

5-(4-{2-[(5-hydroxypyridin-2-yl)(methyl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione

Description:

The chemical substance known as 5-(4-{2-[(5-hydroxypyridin-2-yl)(methyl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione, with the CAS number 257883-22-0, is a thiazolidinedione derivative. Thiazolidinediones are a class of compounds known for their role in pharmacology, particularly in the treatment of diabetes due to their insulin-sensitizing properties. This specific compound features a thiazolidine ring, which is characterized by a five-membered heterocyclic structure containing sulfur and nitrogen. The presence of a hydroxypyridine moiety suggests potential interactions with biological targets, possibly influencing its pharmacological activity. The ethoxy and benzyl substituents contribute to its lipophilicity, which may affect its absorption and distribution in biological systems. Overall, this compound's unique structural features may confer specific biological activities, making it a subject of interest in medicinal chemistry and drug development. Further studies would be necessary to elucidate its precise mechanisms of action and therapeutic potential.

Formula: C₁₈H₁₉N₃O₄S

InChI: InChI=1/C18H19N3O4S/c1-21(16-7-4-13(22)11-19-16)8-9-25-14-5-2-12(3-6-14)10-15-17(23)20-18(24)26-15/h2-7,11,15,22H,8-10H2,1H3,(H,20,23,24)

SMILES: CN(CCOc1ccc(cc1)CC1C(=NC(=O)S1)O)c1ccc(cn1)O

5-Hydroxy Roiglitazone HCl

CAS: 257883-22-0

Formula: C₁₈H₁₉N₃O₄S·HCl

Color and Shape: Pale Yellow Solid

Molecular weight: 373.43 36.46

Ref: 4Z-R-082

5-Hydroxy Rosiglitazone

Controlled Product

CAS: 257883-22-0

Applications A metabolite of Rosiglitazone.
References Balton, G.C., et al.: Xenobiotica, 26, 6, 627 (1996),

Formula: C₁₈H₁₉N₃O₄S

Color and Shape: Neat

Molecular weight: 373.43

Ref: TR-H953440