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CAS 257886-01-4

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N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-trityl-D-homoserine

Description:
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-trityl-D-homoserine is a chemical compound that serves as a protecting group in peptide synthesis. It features a homoserine backbone, which is an amino acid derivative, modified with a trityl group and a fluorenylmethoxycarbonyl (Fmoc) moiety. The trityl group provides stability and protection to the hydroxyl functional group of homoserine during synthetic procedures, while the Fmoc group allows for selective deprotection under mild conditions, facilitating the stepwise assembly of peptides. This compound is typically used in solid-phase peptide synthesis, where the protection of functional groups is crucial for the successful formation of peptide bonds. Its structural complexity and the presence of aromatic groups contribute to its stability and solubility in organic solvents. The compound's CAS number, 257886-01-4, allows for easy identification in chemical databases and literature. Overall, it is an important reagent in the field of organic chemistry and peptide synthesis, aiding in the development of various bioactive peptides and proteins.
Formula:C38H33NO5
InChI:InChI=1/C38H33NO5/c40-36(41)35(39-37(42)43-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34)24-25-44-38(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-23,34-35H,24-26H2,(H,39,42)(H,40,41)/t35-/m1/s1
SMILES:c1ccc(cc1)C(c1ccccc1)(c1ccccc1)OCC[C@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • Fmoc-D-Hse(Trt)-OH
  • NALPHA-FMOC-O-TRITYL-D-HOMOSERINE
  • FMOC-D-HOSER(TRT)-OH
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TRITYL-D-HOMOSERINE
  • FMOC-D-HOSER(TRT)-OH ;FMOC-O-TRITYL-D-HOMOSERINE
  • nα-fmoc-o-trityl-d-homoserine
  • (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-trityloxybutanoic acid
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(triphenylmethoxy)butanoic acid
  • D-Homoserine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(triphenylmethyl)-
  • FMOC-O-TRITYL-D-HOMOSERINE
  • See more synonyms
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