CAS 25830-77-7

N-Phthaloyl-L-glutamic anhydride

Description:

N-Phthaloyl-L-glutamic anhydride, with the CAS number 25830-77-7, is a chemical compound derived from L-glutamic acid, characterized by the presence of a phthaloyl group. This compound typically appears as a white to off-white solid and is known for its role as a reagent in organic synthesis, particularly in peptide synthesis and modifications. It is an anhydride, which means it can react with nucleophiles, such as amines, to form amides. The presence of the phthaloyl group enhances its reactivity and solubility in organic solvents. N-Phthaloyl-L-glutamic anhydride is also utilized in the preparation of various derivatives and can serve as a protecting group for amino acids in peptide synthesis. Its stability under standard laboratory conditions makes it a valuable compound in synthetic organic chemistry. However, as with many chemical substances, appropriate safety measures should be taken when handling it, as it may pose health risks if inhaled or ingested.

Formula: C₁₃H₉NO₅

InChI: InChI=1/C13H9NO5/c15-10-6-5-9(13(18)19-10)14-11(16)7-3-1-2-4-8(7)12(14)17/h1-4,9H,5-6H2/t9-/m0/s1

InChI key: InChIKey=ICDLEMPZXFCQEB-VIFPVBQESA-N

SMILES: O=C1N(C(=O)C=2C1=CC=CC2)[C@@H]3C(=O)OC(=O)CC3

Synonyms:

• 1H-Isoindole-1,3(2H)-dione 2-[(3S)-tetrahydro-2,6-dioxo-2H-pyran-3-yl]-
• 1H-Isoindole-1,3(2H)-dione, 2-(tetrahydro-2,6-dioxo-2H-pyran-3-yl)-, (S)-
• 2-[(3S)-2,6-Dioxooxan-3-yl]-2,3-dihydro-1H-isoindole-1,3-dione
• 2-[(3S)-2,6-Dioxooxan-3-yl]isoindole-1,3-dione
• 2-[(3S)-2,6-dioxotetrahydro-2H-pyran-3-yl]-1H-isoindole-1,3(2H)-dione
• 2-[(3S)-Tetrahydro-2,6-dioxo-2H-pyran-3-yl]-1H-isoindole-1,3(2H)-dione
• <span class="text-smallcaps">L</span>-N-Phthalylglutamic anhydride
• Glutaric anhydride, 2-phthalimido-, <span class="text-smallcaps">L</span>-
• N-Phthaloyl-<span class="text-smallcaps">L</span>-glutamic acid anhydride
• N-Phthaloyl-<span class="text-smallcaps">L</span>-glutamic anhydride
• N-Phthaloyl-<span class="text-smallcaps">L</span>-glutamoyl anhydride
• N-Phthalyl-<span class="text-smallcaps">L</span>-glutamic anhydride
• Phthaloyl-L-glutamic anhyride
• Glutaric anhydride, 2-phthalimido-, L-
• Glutaric anhydride, 2-phthalimido-, L-(-)-
• Pht-L-Glu-anhydride
• PHTHALOYL-L-GLUTAMIC ACID ANHYDRIDE
• PHTHALYL-L-GLUTAMIC ACID ANHYDRIDE
• N,N-Phthaloyl-L-glutamic anhydride
• Phthaloylglutamicanhyride
• -Phthaloyl-
• N-PHTHALYL-L-GLUTAMIC ANHYDRIDE
• -2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)
• N
• PHT-GLU-ANHYDRIDE
• N-PHTHALOYL-L-GLUTAMIC ANHYDRIDE
• 3β-Phthalimidyl-3,4-dihydro-2H-pyran-2,6(5H)-dione
• -glutamic Anhydride
• L

Phthaloyl-L-Glutamic Anhydride

CAS: 25830-77-7

Formula: C₁₃H₉NO₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 259.2143

Ref: IN-DA003TRT

(S)-2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione

CAS: 25830-77-7

(S)-2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione

Purity: 98%

Molecular weight: 259.21g/mol

Ref: 54-OR79351

Phthaloyl-L-glutamic acid anhydride

CAS: 25830-77-7

Molecular weight: 259.21

Ref: 7W-GM7264

(S)-2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione

CAS: 25830-77-7

Purity: 95%

Molecular weight: 259.2170104980469

Ref: 10-F626334

N-Phthaloyl-L-glutamic Anhydride

CAS: 25830-77-7

Formula: C₁₃H₉NO₅

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 259.22

Ref: 3B-P0620

Phthaloyl-L-glutamic acid anhydride

CAS: 25830-77-7

Formula: C₁₃H₉NO₅

Purity: 99.0%

Molecular weight: 259.217

Ref: 10-F510197

N-Phthaloyl-L-glutamic Anhydride

Controlled Product

CAS: 25830-77-7

Applications N-Phthaloyl-L-glutamic Anhydride has been used as a reactant in the synthetic preparation of L-γ-glutamyl-S-(1,2-dichlorovinyl)-L-cysteine which was used to study renal function in pentobarbital-anesthetized dogs.
References Ridgewell, R.E., Krejci, M.E., Koechel, D.A.: Am. J. Vet. Res., 53, 840 (1992)

Formula: C₁₃H₉NO₅

Color and Shape: Neat

Molecular weight: 259.21

Ref: TR-P394400