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CAS 258345-41-4

:

GW 409544

Description:
GW 409544 is a synthetic compound that acts as a selective agonist for the peroxisome proliferator-activated receptor gamma (PPARγ), which is a type of nuclear receptor involved in the regulation of glucose and lipid metabolism. This compound is primarily studied for its potential therapeutic applications in conditions such as type 2 diabetes and obesity, as it may enhance insulin sensitivity and promote adipocyte differentiation. GW 409544 exhibits high selectivity for PPARγ compared to other PPAR subtypes, which may reduce the risk of side effects associated with broader PPAR activation. In terms of its chemical structure, GW 409544 features a distinct arrangement of functional groups that contribute to its biological activity. The compound is typically evaluated in preclinical studies to assess its pharmacokinetics, efficacy, and safety profile. As with many investigational drugs, further research is necessary to fully understand its therapeutic potential and any associated risks.
Formula:C31H30N2O5
InChI:InChI=1S/C31H30N2O5/c1-21(19-29(34)24-9-5-3-6-10-24)32-28(31(35)36)20-23-13-15-26(16-14-23)37-18-17-27-22(2)38-30(33-27)25-11-7-4-8-12-25/h3-16,19,28,32H,17-18,20H2,1-2H3,(H,35,36)/b21-19-/t28-/m0/s1
InChI key:InChIKey=GGUVRMBIEPYOKL-WMVCGJOFSA-N
SMILES:C(COC1=CC=C(C[C@H](N/C(=C\C(=O)C2=CC=CC=C2)/C)C(O)=O)C=C1)C=3N=C(OC3C)C4=CC=CC=C4
Synonyms:
  • L-Tyrosine, N-[(1Z)-1-methyl-3-oxo-3-phenyl-1-propenyl]-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-
  • N-[(1Z)-1-Methyl-3-oxo-3-phenyl-1-propen-1-yl]-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-L-tyrosine
  • L-Tyrosine, N-[(1Z)-1-methyl-3-oxo-3-phenyl-1-propen-1-yl]-O-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-
  • GW 9544
  • GW 409544
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