CAS 25876-10-2

Gentamicin C1

Description:

Gentamicin C1 is an aminoglycoside antibiotic derived from the bacterium Micromonospora purpurea. It is primarily used to treat serious infections caused by Gram-negative bacteria, particularly in cases where other antibiotics are ineffective. Gentamicin C1 exhibits a broad spectrum of antibacterial activity, targeting bacterial ribosomes to inhibit protein synthesis, which ultimately leads to cell death. This compound is characterized by its solubility in water, making it suitable for parenteral administration. Its chemical structure includes multiple amino groups, contributing to its basicity and interaction with bacterial cell membranes. Gentamicin C1 is often administered in clinical settings for infections such as sepsis, respiratory tract infections, and urinary tract infections. However, its use is associated with potential nephrotoxicity and ototoxicity, necessitating careful monitoring of drug levels in patients. Overall, Gentamicin C1 remains a critical therapeutic agent in the management of severe bacterial infections, particularly in hospital settings.

Formula: C₂₁H₄₃N₅O₇

InChI: InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+/m1/s1

InChI key: InChIKey=CEAZRRDELHUEMR-CAMVTXANSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@]([C@H](NC)C)(CC[C@H]2N)[H])[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3

Synonyms:

• O-2-Amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-α-D-ribo-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-D-streptamine
• D-Streptamine, O-2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-α-D-ribo-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-
• Gentamicin C1

Gentamicin C1 pentaacetate salt

CAS: 25876-10-2

Formula: C₃₁H₆₃N₅O₁₇

Purity: ≥ 98%

Color and Shape: White to off-white solid

Molecular weight: 777.86

Ref: 7W-GA1270

Gentamicin C1 Pentaacetate Salt

CAS: 25876-10-2

Formula: C₃₁H₆₃N₂₅O₁₇·5C₂H₄O₂

Molecular weight: 477.60 5*60.05

Ref: 4Z-G-044006

Gentamicin C1 Pentaacetate Salt

CAS: 25876-10-2

Stability Very Hygroscopic
Applications Antibacterial.
References Holt, H.A., et al.: J. Antimicrob. Chemother., 34, 747 (1994), Wilschanski, M., et al.: Am. J. Respir. Crit. Care Med., 161, 860 (2000),

Formula: C₂₁H₄₃N₅O₇·5C₂H₄O₂

Color and Shape: Light Yellow

Molecular weight: 777.86

Ref: TR-G360585

Gentamicin C1

CAS: 25876-10-2

Formula: C₂₁H₄₃N₅O₇

Molecular weight: 477.6

Ref: ST-EA-CP-G33011

Gentamicin C1 pentaacetate

CAS: 25876-10-2

Gentamicin C1 pentaacetate is an aminoglycoside antibiotic with action on bacterial protein synthesis inhibition and is used for research and analytical applications.

Formula: C₂₁H₄₃N₅O₇•(C₂H₄O₂)₅

Purity: Min. 90%

Color and Shape: Off-White Powder

Molecular weight: 777.86 g/mol

Ref: 3D-AG16457

Gentamicin C1

CAS: 25876-10-2

Gentamicin C1 is a broad-spectrum aminoglycoside antibiotic with antibacterial activity.

Formula: C₂₁H₄₃N₅O₇

Color and Shape: Solid

Molecular weight: 477.595

Ref: TM-TN10221