CAS 25876-54-4

(7S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-7-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Description:

The chemical substance with the name "(7S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-7-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one" and CAS number "25876-54-4" is a synthetic steroid compound. It features a complex polycyclic structure typical of steroids, characterized by multiple chiral centers that contribute to its stereochemistry. The presence of hydroxyl (-OH) and ketone (=O) functional groups indicates potential for hydrogen bonding and reactivity, influencing its biological activity. This compound is often studied for its pharmacological properties, particularly in relation to its effects on hormonal pathways and potential therapeutic applications. Its unique side chain, consisting of a dimethylhexyl group, may enhance lipophilicity, affecting its absorption and distribution in biological systems. Overall, this compound exemplifies the intricate relationship between molecular structure and biological function in steroid chemistry.

Formula: C₂₇H₄₄O₂

InChI: InChI=1/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h15,17-18,21-25,29H,6-14,16H2,1-5H3/t18-,21-,22+,23+,24+,25?,26+,27-/m1/s1

7β-Hydroxy-4-cholesten-3-one

Controlled Product

CAS: 25876-54-4

Applications A metabolite of Cholesterol.
References Connor, W., et al.: J, Clin. Invest., 48, 1363 (1969), Nestel, P., et al.: Metabolism, 24, 189 (1975), Ellegard, L., et al.: Eur. J. Clin. Nutr., 45, 451 (1991), Pedersen, A., et al.: J. Lipid Res., 41, 1901 (2000),

Formula: C₂₇H₄₄O₂

Color and Shape: Neat

Molecular weight: 400.64

Ref: TR-H825125

7b-Hydroxy-4-cholesten-3-one

Controlled Product

CAS: 25876-54-4

7b-Hydroxy-4-cholesten-3-one is a naturally occurring bile acid that is involved in the metabolism of cholesterol, fat and vitamin D. It has been shown to be beneficial in the treatment of cerebrotendinous xanthomatosis, which is characterized by an accumulation of cholesterol and fatty acids in the brain and spinal cord. The drug also regulates cell signaling pathways, such as those related to energy metabolism. 7b-Hydroxy-4-cholesten-3-one is synthesized from 7a-hydroxycholesterol in humans, but not other mammals. It is metabolized via oxidation by cytochrome P450 enzymes or conjugation with glucuronic acid.

Formula: C₂₇H₄₄O₂

Purity: Min. 95%

Molecular weight: 400.64 g/mol

Ref: 3D-FH24258