CAS 2588445-14-9

4-Pyrimidinecarboxamide, 2-[[(S)-(2-chlorophenyl)(3-cyanophenyl)methyl]methylamino]-1,6-dihydro-5-hydroxy-N-4-isoxazolyl-1-methyl-6-oxo-

Description:

4-Pyrimidinecarboxamide, 2-[[(S)-(2-chlorophenyl)(3-cyanophenyl)methyl]methylamino]-1,6-dihydro-5-hydroxy-N-4-isoxazolyl-1-methyl-6-oxo- is a complex organic compound characterized by its multi-functional structure, which includes a pyrimidine ring, an isoxazole moiety, and various aromatic substituents. This compound is likely to exhibit properties typical of amides, such as potential solubility in polar solvents and the ability to form hydrogen bonds due to the presence of hydroxyl and amine groups. The presence of chlorophenyl and cyanophenyl groups suggests that it may have significant biological activity, possibly as a pharmaceutical agent. The stereochemistry indicated by the (S) configuration implies specific spatial arrangements that could influence its interaction with biological targets. Additionally, the compound's molecular weight, melting point, and other physical properties would be influenced by its intricate structure, which may also affect its stability and reactivity under various conditions. Overall, this compound represents a class of molecules that may have applications in medicinal chemistry and drug development.

Formula: C₂₄H₁₉ClN₆O₄

Synonyms:

• 4-Pyrimidinecarboxamide, 2-[[(S)-(2-chlorophenyl)(3-cyanophenyl)methyl]methylamino]-1,6-dihydro-5-hydroxy-N-4-isoxazolyl-1-methyl-6-oxo-

TREX1-IN-4

CAS: 2588445-14-9

TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.

Formula: C₂₄H₁₉ClN₆O₄

Color and Shape: Solid

Molecular weight: 490.898

Ref: TM-T205208