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CAS 2591588-58-6

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  • Rugonersen sodium

    CAS:
    Rugonersen sodium is a locked nucleic acid (LNA)-modified antisense oligonucleotide (ASO) designed to reduce the silencing of ubiquitin protein ligase E3A (UBE3A). Angelman syndrome (AS) refers to a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, and Rugonersen has been studied for its potential use in the treatment of AS.
    Formula:C204H235N63Na19O109P19S19
    Molecular weight:6948.00