CAS 259212-61-8: (4R)-4-{[tert-butyl(diphenyl)silyl]oxy}-L-proline
Description:(4R)-4-{[tert-butyl(diphenyl)silyl]oxy}-L-proline, with CAS number 259212-61-8, is a synthetic amino acid derivative characterized by its unique structural features. This compound contains a proline backbone, which is a cyclic amino acid known for its role in protein structure and stability. The presence of a tert-butyl(diphenyl)silyl group enhances its hydrophobic properties and provides steric bulk, which can influence its reactivity and interactions in biological systems. The specific stereochemistry at the 4-position (designated as (4R)) is crucial for its biological activity, as chirality can significantly affect the compound's behavior in enzymatic reactions and binding to receptors. Additionally, the silyl ether functionality may serve as a protective group in synthetic applications, allowing for selective reactions. Overall, this compound is of interest in medicinal chemistry and peptide synthesis, where modifications to amino acids can lead to novel therapeutic agents or tools for studying biological processes.
Formula:C21H27NO3Si
InChI:InChI=1/C21H27NO3Si/c1-21(2,3)26(17-10-6-4-7-11-17,18-12-8-5-9-13-18)25-16-14-19(20(23)24)22-15-16/h4-13,16,19,22H,14-15H2,1-3H3,(H,23,24)/t16-,19+/m1/s1
- Synonyms:
- L-proline, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, (4R)-