CAS 259731-39-0

Cyclobutanemethanamine, 1-(4-chlorophenyl)-N-methyl-α-(2-methylpropyl)-, hydrochloride (1:1), (αS)-

Description:

Cyclobutanemethanamine, 1-(4-chlorophenyl)-N-methyl-α-(2-methylpropyl)-, hydrochloride (1:1), (αS)- is a chemical compound characterized by its specific structural features and functional groups. It contains a cyclobutane ring, which contributes to its cyclic structure, and an amine functional group, indicating its potential basicity and ability to form salts, such as the hydrochloride form. The presence of a 4-chlorophenyl group suggests that it may exhibit aromatic properties, while the N-methyl and α-(2-methylpropyl) substituents indicate steric hindrance and possible influence on its biological activity. The hydrochloride salt form enhances its solubility in water, making it more suitable for various applications, including pharmaceutical uses. The compound's stereochemistry, indicated by the (αS) designation, suggests specific spatial arrangements of its atoms, which can significantly affect its reactivity and interaction with biological targets. Overall, this compound's unique combination of cyclic structure, functional groups, and stereochemistry may contribute to its potential utility in medicinal chemistry and related fields.

Formula: C₁₆H₂₄ClN·ClH

InChI: InChI=1S/C16H24ClN.ClH/c1-12(2)11-15(18-3)16(9-4-10-16)13-5-7-14(17)8-6-13;/h5-8,12,15,18H,4,9-11H2,1-3H3;1H/t15-;/m0./s1

InChI key: InChIKey=OUVFHVJVFLFXPQ-RSAXXLAASA-N

SMILES: [C@@H](CC(C)C)(NC)C1(CCC1)C2=CC=C(Cl)C=C2.Cl

Synonyms:

• (S)-Desmethylsibutramine hydrochloride
• Cyclobutanemethanamine, 1-(4-chlorophenyl)-N-methyl-α-(2-methylpropyl)-, hydrochloride, (αS)-
• Cyclobutanemethanamine,1-(4-chlorophenyl)-N-methyl-a-(2-methylpropyl)-, hydrochloride, (aS)- (9CI)
• Cyclobutanemethanamine, 1-(4-chlorophenyl)-N-methyl-α-(2-methylpropyl)-, hydrochloride (1:1), (αS)-

(S)​-​Desmethyl Sibutramine Hydrochloride

Controlled Product

CAS: 259731-39-0

Applications (S)​-​Desmethyl Sibutramine Hydrochloride is a metabolite of Sibutramine (S422500), a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.
References Hanotin, C., et al.: Int. J. Obesity, 22, 32 (1998); Woolard, J., et al.: J. Pharmacol. Exp. Ther., 308, 1102 (2004); Geranton, S., et al.: Neuropharmacol., 46, 511 (2004)

Formula: C₁₆H₂₄ClN·HCl

Color and Shape: Neat

Molecular weight: 265.83 + (36.46)

Ref: TR-D291925