CAS 259869-55-1
:JWH 133
Description:
JWH-133 is a synthetic cannabinoid that belongs to a class of compounds known as indole derivatives. It was developed by John W. Huffman and is primarily known for its agonistic activity at cannabinoid receptors, particularly CB1 and CB2. This compound is characterized by its ability to mimic the effects of natural cannabinoids found in cannabis, such as THC. JWH-133 is often studied for its potential therapeutic applications, including pain relief and anti-inflammatory effects, although it is not approved for medical use. Its chemical structure includes a naphthalene ring and an indole moiety, contributing to its binding affinity and selectivity for cannabinoid receptors. As a research chemical, JWH-133 is typically encountered in laboratory settings and is not intended for human consumption. Due to its psychoactive properties, it is subject to regulatory scrutiny in many jurisdictions, and its safety profile is not well established, necessitating caution in its handling and use.
Formula:C22H32O
InChI:InChI=1S/C22H32O/c1-7-12-21(3,4)16-9-10-17-18-13-15(2)8-11-19(18)22(5,6)23-20(17)14-16/h8-10,14,18-19H,7,11-13H2,1-6H3/t18-,19+/m0/s1
InChI key:InChIKey=YSBFLLZNALVODA-RBUKOAKNSA-N
SMILES:CC1(C)[C@]2([C@](C=3C(=CC(C(CCC)(C)C)=CC3)O1)(CC(C)=CC2)[H])[H]
Synonyms:- (6AR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene
- (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran
- (6aR,10aR)-6,6,9-Trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene
- 6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-, (6aR,10aR)-
- Jw 133
- Jwh-133
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Found 5 products.
JWH 133
CAS:Controlled Product<p>An agonist of cannabinoid CB2 receptors. Reduces cardiac infarct size, mediated by inhibiting intrinsic mitochondria-mediated apoptosis in the myocardium during ischemia/reperfusion. Reversal of the cardioprotective activity of JWH 133 by wortmanin suggests the involvement of PI3K/Akt signalling pathway.</p>Formula:C22H32OPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:312.49 g/mol



