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CAS 25988-63-0

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poly-L-lysine hydrobromide

Description:
Poly-L-lysine hydrobromide is a synthetic polypeptide composed of the amino acid lysine, characterized by its cationic nature due to the presence of amino groups that can be protonated. This polymer is typically used in various applications, including drug delivery, gene therapy, and as a coating agent in biomedical devices due to its biocompatibility and ability to interact with negatively charged molecules, such as DNA and cell membranes. Poly-L-lysine hydrobromide is soluble in water, and its solubility can be influenced by factors such as pH and ionic strength. The hydrobromide form enhances its stability and solubility in aqueous solutions. Additionally, it exhibits antimicrobial properties, making it useful in various pharmaceutical and cosmetic formulations. The molecular weight of poly-L-lysine can vary depending on the degree of polymerization, which influences its physical and chemical properties. Overall, poly-L-lysine hydrobromide is a versatile compound with significant applications in the fields of biotechnology and materials science.
Formula:C6H15BrN2O2
InChI:InChI=1/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
InChI key:InChIKey=MEXAGTSTSPYCEP-JEDNCBNOSA-N
SMILES:[C@H](CCCCN)(C(O)=O)N.Br
Synonyms:
  • Lysine, L-, peptides, hydrobromide
  • Poly(L-lysine) hydrobromide
  • Poly-L-lysine hydrogen bromide
  • L-Lysine, homopolymer, hydrobromide
  • Polylysine hydrobromide
  • Poly-L-Lysine Hydrobromide [MW 1, 500-8, 000]
  • L-Lysine homopolymer
  • POLY-L-LYSINE HYDROBROMIDE, MOL WT 7
  • Poly-L-lysine HBr
  • POLY-L-LYSINE HYDROBROMIDE MOL. WT.*70,0 00-150,000
  • See more synonyms
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Found 8 products.
  • L-Lysine, homopolymer, hydrobromide

    CAS:
    Formula:C10H27BrN2O
    Purity:%
    Color and Shape:Solid
    Molecular weight:271.2382

    Ref: IN-DA002RBE

    1g
    29.00€
    5g
    50.00€
    25g
    106.00€
    100g
    212.00€
    250mg
    25.00€
  • Poly-L-Lysine Hydrobromide

    CAS:
    Poly-L-Lysine Hydrobromide
    Purity:MW3000-5000

    Ref: 54-OR1014789

    1g
    32.00€
    5g
    36.00€
    25g
    89.00€
    100g
    240.00€
    500g
    754.00€
    2.5kg
    2,214.00€
  • Poly-L-Lysine Hydrobromide

    CAS:
    <p>Poly-L-Lysine Hydrobromide is a neurotrophic factor that is used to stimulate nerve growth in the peripheral nervous system. It has been shown to increase the production of nerve growth factor, which is important for neuronal development and regeneration. Poly-L-Lysine Hydrobromide also has biological properties against human erythrocytes, enabling it to bind to the erythrocyte membrane and subsequently cause hemolysis. This process is mediated by Toll-like receptors. The active form of this drug has been shown to have antiviral activity against HIV and other viruses in transfection experiments using cells from mice, as well as an ability to inhibit replication of herpes simplex virus type 1 (HSV-1) in a model system consisting of rat neurons grown on a polymer substrate. Poly-L-Lysine Hydrobromide can be cleaved into smaller pieces by enzymes such as DNase I or terminal transferases, forming polymers</p>
    Purity:Min. 95%

    Ref: 3D-OKK-3056

    1g
    478.00€
    100mg
    190.00€
  • Poly-L-lysine hydrobromide - M.W:4000-20000

    CAS:
    <p>Poly-L-Lysine hydrobromide is a synthetic polymer that is used as a bacterial sealant, a model system for studying the effects of antimicrobial peptides on cells and as an additive to human serum. It has been shown to inhibit the growth of carcinoma cell lines and it has been used in treatments for leukemic mice. The molecular weight of this polymer ranges from 4000 to 20000. Poly-L-Lysine hydrobromide contains terminal amide groups, which can be cleaved by trypsin, an enzyme found in soybean and human serum. This allows it to act as a carrier molecule for other molecules.</p>
    Formula:(C6H14N2O2)x•(HBr)x
    Purity:Min. 95%
    Color and Shape:White Powder

    Ref: 3D-FP177958

    25mg
    220.00€
    50mg
    372.00€
    100mg
    588.00€
    250mg
    976.00€
    500mg
    1,184.00€
  • Poly-L-lysine hydrobromide - M.W:70000-150000

    CAS:
    <p>Poly-L-lysine hydrobromide is a synthetic polymer that is used as a coating material for medical devices and implants. Poly-L-lysine hydrobromide has been shown to have antimicrobial activity against leukemic mice, carcinoma cell lines, and other microorganisms. It also has been shown to inhibit the growth of bacteria in vitro by binding to their cell membranes and interfering with their metabolism. This polymer has been shown to be effective in treating bacterial infections on the skin, urinary tract, and respiratory system. Poly-L-lysine hydrobromide has also been used as a coating material for catheters to prevent biofilm formation, which can lead to urinary tract infections. The carboxy terminal end of the polymer chain renders it hydrophobic and prevents it from precipitating out of solution. The thermal expansion coefficient of poly-L-lysine hydrobromide is very close to that of water, so it will not cause any kind</p>
    Formula:(C6H12N2O2)n•(HBr)x
    Color and Shape:White Powder

    Ref: 3D-FP57749

    1g
    904.00€
    2g
    1,136.00€
    5g
    1,477.00€
    250mg
    358.00€
    500mg
    573.00€
  • Poly-L-lysine hydrobromide - M.W:1000-5000

    CAS:
    <p>Poly-L-lysine hydrobromide is a polymer that consists of repeating lysine monomers. It has a molecular weight range of 1000 to 5000 Daltons. Poly-L-lysine hydrobromide is used for intramolecular hydrogen bonding, which increases its resistance to thermal and kinetic energy. Poly-L-lysine hydrobromide is also used in the structural analysis of proteins, because it can be easily purified from human serum by dialysis. This polymer has been shown to be effective against carcinoma cell lines, amide bonds, terminal residues, and ester linkages. There is also evidence that poly-L-lysine hydrobromide may have anticancer properties in vitro and in vivo.<br>Poly-L-lysine hydrobromide has been shown to have antiangiogenic properties due to its ability to block the interaction between tumor cells and endothelial cells. This can lead to tumor regression and decreased metastasis</p>
    Formula:(C6H12N2O2)n•(HBr)x
    Purity:Min. 95%
    Color and Shape:White Powder

    Ref: 3D-FP166353

    25mg
    220.00€
    50mg
    372.00€
    100mg
    588.00€
    250mg
    976.00€
    500mg
    1,115.00€
  • Poly-L-Lysine Hydrobromide (PLL HBr), 70-150kDa

    CAS:
    Formula:LLys(LLys)nLLys·xHBr
    Color and Shape:White to off-white, Solid, Colourless to faint yellow, Clear to slightly hazy
    Molecular weight:70,000-150,000

    Ref: SR-54422

    25mg
    79.00€
    100mg
    266.00€
    250mg
    579.00€
  • Poly-L-lysine hydrobromide - M.W:15,000-30,000

    CAS:
    <p>Poly-L-lysine hydrobromide is a polypeptide made of lysine and has a molecular weight of 15,000 to 30,000. It has been shown to have antimicrobial properties and has been used as an additive in animal feed. This product has been shown to be effective against leukemic mice as well as carcinoma cell lines. Poly-L-lysine hydrobromide is also known to inhibit the activity of glycol ester hydrolase, which is an enzyme that catalyzes the hydrolysis of glycol esters. The carboxy terminal amino acid residues on this molecule are in the form of an amide bond with a protein.</p>
    Formula:(C6H12N2O2)n•(HBr)x
    Purity:Min. 95%

    Ref: 3D-FP170218

    25mg
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    100mg
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    250mg
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    500mg
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