CAS 25999-20-6

Lasalocid sodium

Description:

Lasalocid sodium is a polyether ionophore antibiotic primarily used as a feed additive in livestock to promote growth and improve feed efficiency. It is characterized by its ability to transport monovalent cations, such as sodium and potassium, across biological membranes, which can alter ion balance and influence cellular processes. This compound is typically presented as a white to off-white powder and is soluble in organic solvents but has limited solubility in water. Lasalocid sodium exhibits antimicrobial properties, particularly against certain Gram-positive bacteria and protozoa, making it effective in controlling coccidiosis in poultry and other livestock. Its mechanism of action involves disrupting ion homeostasis in target organisms, leading to their inhibition or death. While it is generally regarded as safe for use in animals, there are regulatory limits on its application in food-producing animals to ensure consumer safety. Additionally, its use is subject to scrutiny due to potential environmental impacts and the development of resistance in microbial populations.

Formula: C₃₄H₅₄O₈·Na

InChI: InChI=1S/C34H54O8.Na/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39;/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39);/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+;/m1./s1

InChI key: InChIKey=JCKLHIQQJWLHGH-HWLWSTNVSA-N

SMILES: C(C)[C@@]1(O[C@]([C@H](C([C@H]([C@H]([C@@H](CCC2=C(C(O)=O)C(O)=C(C)C=C2)C)O)C)=O)CC)([C@@H](C)C1)[H])[C@@]3(O[C@@H](C)[C@](CC)(O)CC3)[H].[Na]

Synonyms:

• (1S,9S)-1,4:5,9-dianhydro-1-[(1S,3R,4R,5R)-7-(2-carboxy-3-hydroxy-4-methylphenyl)-1-ethyl-4-hydroxy-3,5-dimethyl-2-oxoheptyl]-2,3,6,7-tetradeoxy-4-ethyl-8-C-ethyl-2,9-dimethyl-D-gluco-nonitol
• (1S,9S)-1,5:6,9-dianhydro-9-[(1R,3S,4S,5R)-7-(2-carboxy-3-hydroxy-4-methylphenyl)-1-ethyl-4-hydroxy-3,5-dimethyl-2-oxoheptyl]-3,4,7,8-tetradeoxy-6-ethyl-2-C-ethyl-1,8-dimethyl-D-galacto-nonitol
• 2,3-Cresotic acid, 6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-, monosodium salt. (-)-
• 6-(7-(5-Ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methylbenzoic acid monosodium salt, (2R-(2alpha(2S*(3R*,4S*,5S*,7R*),3S*,5S*),5alpha,6beta))-
• Avatec
• Benzoic acid, 6-((3R,4S,5S,7R)-7-((2S,3S,5S)-5-ethyl-5-((2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methyl-, monosodium salt
• Benzoic acid, 6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methyl-, monosodium salt, (2R-(2alpha(2S*(3R*,4S*,5S*,7R*),3S*,5S*),5alpha,6beta))-
• Benzoic acid, 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methyl-, monosodium salt
• Benzoic acid, 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methyl-, sodium salt (1:1)
• Bovate 20
• Bovatec
• Bovatec 150FP
• Lasalocid A monosodium salt
• Lasalocid sodium
• Lasalocid sodium salt
• Mt 2007
• Nsc 243046
• Ro 2-2985
• Sodium lasalocid
• Sodium lasalocid A
• Unii-W2S5C71Y3G
• sodium 1,4:5,9-dianhydro-1-[9-(2-carboxylato-3-hydroxy-4-methylphenyl)-6-hydroxy-5,7-dimethyl-4-oxononan-3-yl]-2,3,6,7-tetradeoxy-4-ethyl-8-C-ethyl-2,9-dimethylnonitol

Lasalocid sodium

CAS: 25999-20-6

Lasalocid sodium, an antibiotic from Streptomyces lasaliensis, regulates calcium in muscles and is used as a poultry coccidiostat.

Formula: C₃₄H₅₃NaO₈

Purity: 97.08% - 99.58%

Color and Shape: Solid

Molecular weight: 612.77

Ref: TM-T15716

Lasalocid sodium

CAS: 25999-20-6

Lasalocid sodium

Purity: ≥95%

Molecular weight: 612.77g/mol

Ref: 54-BUP13275

Lasalocid A Sodium Salt

CAS: 25999-20-6

Formula: C₃₄H₅₃O₈·Na

Molecular weight: 589.79 22.99

Ref: 4Z-L-110002

Lasalocid A sodium 100 µg/mL in Acetonitrile

CAS: 25999-20-6

Formula: C₃₄H₅₃O₈·Na

Color and Shape: Single Solution

Molecular weight: 612.77

Ref: 04-XA14593000AL

Lasalocid A sodium

Controlled Product

CAS: 25999-20-6

Formula: C₃₄H₅₃O₈·Na

Color and Shape: Neat

Molecular weight: 612.77

Ref: 04-C14593000

Lasalocid A sodium salt Solution, ~100 µg/ml in acetonitrile

CAS: 25999-20-6

Ref: 7W-GW0266

Lasalocid A sodium salt

CAS: 25999-20-6

Formula: C₃₄H₅₃NaO₈

Purity: ≥ 97%

Color and Shape: White to off-white solid

Molecular weight: 612.77

Ref: 7W-GW9729

Lasalocid A Sodium Salt

Controlled Product

CAS: 25999-20-6

Applications Lasalocid A Sodium Salt is a coccidiostat (for poultry).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shimoda, M., et al.: J. Food Sci., 59, 231 (1994); Robinson, B., et al.: Biochem. Med. Metab. Biol., 48, 122 (1992); Lesnefsky, E., et al.: J. Biol. Chem., 279, 47961 (2004)

Formula: C₃₄H₅₃O₈·Na

Purity: >90%

Color and Shape: Off-White To Beige

Molecular weight: 612.77

Ref: TR-L177805

Lasalocid A sodium salt

CAS: 25999-20-6

Lasalocid is a water-soluble sodium salt of lasalocid A, an antimicrobial agent that is used in wastewater treatment. Lasalocid A has been shown to have effects on the enzyme activities of quillaja saponaria, which may be due to its ability to change the phase transition temperature and react with enzymes involved in energy metabolism. Lasalocid A also appears to have cardiotoxic effects when administered in high doses in experimental models. The potential for toxicity is decreased when it is combined with dopamine β-hydroxylase inhibitors such as carbidopa.

Formula: C₃₄H₅₃NaO₈

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 612.77 g/mol

Ref: 3D-FL158985

Lasalocid A sodium salt - 0.1mg/ml, in acetonitrile

CAS: 25999-20-6

Lasalocid A sodium salt is a sodium salt of lasalocid, which is a macrolide antibiotic that inhibits bacterial growth by binding to the 50S ribosomal subunit. Lasalocid A sodium salt has intramolecular hydrogen bonds and exhibits high solubility in acetonitrile. The experimental solubility data was obtained using an analytical method with quillaja saponaria as a model system. Lasalocid A sodium salt has been used as an experimental model for congestive heart failure and is also used in biological samples such as blood, urine, or tissue. This drug is highly resistant to degradation by bacteria.

Formula: C₃₄H₅₃NaO₈

Purity: Min. 90 Area-%

Color and Shape: Colorless Clear Liquid

Molecular weight: 612.77 g/mol

Ref: 3D-FL24845

Lasalocid A Sodium Salt (Solution in acetonitrile 0.1mg/ml) (>90%)

Controlled Product

CAS: 25999-20-6

Formula: C₃₄H₅₃O₈·Na

Purity: >90%

Color and Shape: Single Solution

Molecular weight: 612.77

Ref: TR-L177800

Lasalocid A sodium 100 µg/mL in Methanol

CAS: 25999-20-6

Formula: C₃₄H₅₃O₈·Na

Color and Shape: Single Solution

Molecular weight: 612.77

Ref: 04-A14593000ME-100