CAS 26001-38-7

8-Mercaptoguanosine

Description:

8-Mercaptoguanosine is a nucleoside derivative characterized by the presence of a thiol (-SH) group at the 8-position of the guanine base. This modification imparts unique chemical properties, including increased reactivity and potential for forming disulfide bonds. The substance is soluble in water and exhibits a polar nature due to the presence of both the guanine base and the ribose sugar. It plays a role in various biochemical processes, particularly in the context of nucleic acid metabolism and signaling pathways. The thiol group can participate in redox reactions, making 8-mercaptoguanosine of interest in studies related to oxidative stress and cellular signaling. Additionally, its structural similarity to other nucleosides allows it to interact with nucleic acid structures, potentially influencing their stability and function. Overall, 8-mercaptoguanosine serves as a valuable compound in biochemical research, particularly in the fields of molecular biology and medicinal chemistry.

Formula: C₁₀H₁₃N₅O₅S

InChI: InChI=1/C10H13N5O5S/c11-9-13-6-3(7(19)14-9)12-10(21)15(6)8-5(18)4(17)2(1-16)20-8/h2,4-5,8,16-18H,1H2,(H,12,21)(H3,11,13,14,19)

InChI key: InChIKey=KZELNMSPWPFAEB-UMMCILCDSA-N

SMILES: S=C1N(C2=C(N1)C(=O)N=C(N)N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O

Synonyms:

• 8-Thioguanosine
• Guanosine, 8-mercapto-
• Guanosine, 7,8-dihydro-8-thioxo-
• 7,8-Dihydro-8-thioxoguanosine
• 8-Mercaptoguanosine
• 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-thioxo-8,9-dihydro-1H-purin-6(7H)-one
• Nsc79216
• 8-Mercapto-7,8-dihydroguanosin
• 8-SH-Guo
• 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-thioxo-1,7,8,9-tetrahydro-6H-purin-6-one
• 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-sulfanylidene-3,7-dihydropurin-6-one
• 8-MERCAPTOGUANOSINE HYDRATE
• SQ 12760

8-Mercaptoguanosine

CAS: 26001-38-7

Formula: C₁₀H₁₃N₅O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 315.3057

Ref: IN-DA002RDD

8-Mercaptoguanosine

CAS: 26001-38-7

8-Mercaptoguanosine

Purity: 98%

Ref: 54-OR1037458

8-Mercaptoguanosine

CAS: 26001-38-7

Formula: C₁₀H₁₃N₅O₅S

Purity: ≥ 95.0%

Color and Shape: White crystalline solid

Molecular weight: 315.30

Ref: 7W-GN1805

8-Thioguanosine

Controlled Product

CAS: 26001-38-7

Stability Hygroscopic
Applications 8-Thioguanosine (cas# 26001-38-7) is a useful research chemical.

Formula: C₁₀H₁₃N₅O₅S

Color and Shape: Neat

Molecular weight: 315.3

Ref: TR-T350788

8-Thioguanosine

CAS: 26001-38-7

8-Thioguanosine is a purine derivative with reactive chlorine atoms. It has been shown to be a potent inhibitor of cellular targets, including monoclonal antibodies, growth factors, and transcription-polymerase chain reactions (PCR). 8-Thioguanosine binds to the antibody response by modulating the function of the B cells. This drug also has immunomodulatory effects that have been shown in animal models. 8-Thioguanosine is used as an immunosuppressant in patients undergoing bone marrow transplants and solid organ transplants.

Formula: C₁₀H₁₃N₅O₅S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 315.3 g/mol

Ref: 3D-NT07601

8-Mercaptoguanosine

CAS: 26001-38-7

Purity: 98%

Molecular weight: 315.06

Ref: 10-F554599