CAS 26016-98-8

Fosfomycin calcium

Description:

Fosfomycin calcium, with the CAS number 26016-98-8, is a broad-spectrum antibiotic that is primarily used to treat urinary tract infections. It is a derivative of phosphonic acid and functions by inhibiting bacterial cell wall synthesis, specifically targeting the enzyme MurA, which is crucial for peptidoglycan formation. This mechanism of action makes it effective against a variety of Gram-positive and Gram-negative bacteria. Fosfomycin calcium is typically administered as a calcium salt to enhance its stability and solubility. The compound is known for its low toxicity profile and is often well-tolerated by patients. It is available in various formulations, including oral and intravenous preparations. In addition to its antibacterial properties, fosfomycin has been investigated for potential use in treating other infections and conditions due to its unique mechanism. However, resistance can develop, so its use is generally reserved for specific indications where other antibiotics may not be effective. Overall, fosfomycin calcium is a valuable agent in the antibiotic arsenal, particularly for uncomplicated urinary tract infections.

Formula: C₃H₇O₄P

InChI: InChI=1/C3H7O4P.Ca/c1-2-3(7-2)8(4,5)6;/h2-3H,1H3,(H2,4,5,6);/q;+2/t2-,3+;/m0./s1

InChI key: InChIKey=XXIDJCLHAMGLRU-LJUKVTEVSA-N

SMILES: P(=O)(O)(O)[C@@H]1[C@H](C)O1.[Ca]

Synonyms:

• (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid
• Calcium (3-Methyloxiran-2-Yl)Phosphonate
• Calcium fosfomycin
• Calcium phosphomycin
• Calcium phosphonomycin
• Fosfomycin Calcium
• Fosfomycin calcium salt
• Fosfomycin calcium salt (1:1)
• Fosmicin
• Levo-phosphonomycin calcium salt
• Phosphomycin calcium salt
• Phosphonic acid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)-
• Phosphonic acid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-cis)-
• Phosphonic acid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-trans)-
• Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, calcium salt (1:1)
• Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (1:1)
• Phosphonomycin calcium salt
• [(2R,3S)-3-Methyloxiranyl]phosphonic acid calcium salt
• calcium [(2R,3S)-3-methyloxiran-2-yl]phosphonate
• calcium [(2S,3R)-3-methyloxiran-2-yl]phosphonate
• calciumphosphonomycin
• (3-methyloxiranyl)-,calciumsalt(1:1),(2r-cis)-phosphonicaci
• PHOSPHOMYCIN CALCIUM SALT MONOHYDRATE
• calciumphosphomycin
• calciumfosfomycin
• FOSFOMYCIN
• (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, Fosfomycin calcium salt, Phosphonomycin
• calcium hydrogen (2R-cis)-(3-methyloxiranyl)phosphonate
• PHOSPHOMYCIN
• phosphomycincalcium
• (1,2-epoxypropyl)-,calciumsalt(1:1),(1r,2s)-(-)-phosphonicaci
• Phosphonic acid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)-(8CI)

Fosfomycin calcium monohydrate

CAS: 26016-98-8

Formula: C₃H₅CaO₄P

Purity: 97%

Color and Shape: Solid

Molecular weight: 176.1212

Ref: IN-DA002REJ

Fosfomycin calcium

CAS: 26016-98-8

Fosfomycin calcium (Phosphomycin calcium salt) is a BBB penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.

Formula: C₃H₅CaO₄P

Purity: 99%

Color and Shape: White Crystal Powder Tasteless

Molecular weight: 176.12

Ref: TM-T3131

Calcium ((2R,3S)-3-Methyloxiran-2-Yl)Phosphonate

CAS: 26016-98-8

Calcium ((2R,3S)-3-Methyloxiran-2-Yl)Phosphonate

Purity: 98%

Molecular weight: 176.12g/mol

Ref: 54-IN12115

Fosfomycin calcium

CAS: 26016-98-8

Fosfomycin calcium

Purity: ≥98%

Molecular weight: 176.12g/mol

Ref: 54-BUP15986

Phosphomycin calcium salt

CAS: 26016-98-8

Formula: C₃H₅O₄PCa

Purity: ≤ 1.5%

Color and Shape: White or almost white powder

Molecular weight: 176.12

Ref: 7W-GA9549

Fosfomycin calcium

Controlled Product

CAS: 26016-98-8

Formula: C₃H₅O₄P·Ca

Color and Shape: Neat

Molecular weight: 176.12

Ref: 04-C13941000

Fosfomycin Calcium

CAS: 26016-98-8

Formula: C₃H₅O₄P·Ca

Molecular weight: 136.04 40.08

Ref: 4Z-F-4741

Fosfomycin Calcium

Controlled Product

CAS: 26016-98-8

Applications Fosfomycin Calcium is a bacterial wall synthesis inhibitor.
References Michalopoulos, A. et al.: Int. J. Infect. Dis., 15, e732 (2011); Matsumoto, T. et al.: J. Infection. Chemother., 17, 80 (2011);

Formula: C₃H₅O₄P·Ca

Color and Shape: Neat

Molecular weight: 176.12

Ref: TR-F727508