CAS 26016-99-9

Fosfomycin sodium

Description:

Fosfomycin sodium is an antibiotic used primarily for the treatment of urinary tract infections. It is a phosphonic acid derivative that acts by inhibiting bacterial cell wall synthesis, specifically targeting the enzyme MurA, which is crucial for peptidoglycan formation. This mechanism makes it effective against a broad spectrum of Gram-positive and Gram-negative bacteria. Fosfomycin sodium is typically administered as a prodrug, which is converted to its active form in the body. It is characterized by its high solubility in water, allowing for easy administration and absorption. The compound is generally well-tolerated, with a low incidence of side effects, although some patients may experience gastrointestinal disturbances or allergic reactions. Its pharmacokinetics include rapid absorption and excretion, with a relatively short half-life, necessitating careful dosing. Fosfomycin sodium is often used in cases of uncomplicated cystitis and is notable for its ability to penetrate biofilms, making it a valuable option in treating resistant infections.

Formula: C₃H₇O₄P·2Na

InChI: InChI=1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/t2-,3+;;/m0../s1

InChI key: InChIKey=XKMSQWKOGZTAQM-JSTPYPERSA-N

SMILES: P(=O)(O)(O)[C@@H]1[C@H](C)O1.[Na]

Synonyms:

• (3-Methyloxiran-2-Yl)Phosphonic Acid
• Disodium fosfomycin
• Disodium phosphonomycin
• FOM-Na
• Forocyle S
• Fosfocin
• Fosfomycin disodium
• Fosfomycin disodium salt
• Fosfomycin sodium
• Fosfomycin sodium salt
• Fosmicin S
• Levo-phosphonomycin disodium salt
• NSC 136017
• Phosphomycin Disodium
• Phosphomycin sodium
• Phosphonic acid, (1,2-epoxypropyl)-, disodium salt, (1R,2S)-(-)-
• Phosphonic acid, (3-methyloxiranyl)-, disodium salt, (2R-cis)-
• Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, sodium salt (1:2)
• Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, disodium salt
• Phosphonomycin disodium salt
• Phosphonomycin sodium
• Sodium fosfomycin

Fosfomycin Disodium Salt

CAS: 23155-02-4, 26016-99-9

Formula: C₃H₅Na₂O₄P

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 182.02

Ref: 3B-F0889

Fosfomycin disodium, 90%

CAS: 26016-99-9

Prevents peptidoglycan synthesis by inhibiting MurA, an enzyme responsible for synthesizing N-acetylmuramic acid or NAM, a major component of peptidoglycan This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information

Formula: C₃H₅Na₂O₄P

Purity: 90%

Molecular weight: 182.02

Ref: 02-J66602

[(2R,3S)-3-methyloxiranyl]phosphonic acid disodium salt

CAS: 26016-99-9

Formula: C₃H₅Na₂O₄P

Purity: 98%

Color and Shape: Solid

Molecular weight: 182.0227

Ref: IN-DA003TR2

Fosfomycin sodium

CAS: 26016-99-9

Fosfomycin sodium

Purity: ≥98%

Molecular weight: 182.02g/mol

Ref: 54-BUP18606

Fosfomycin Disodium Salt

CAS: 26016-99-9

Formula: C₃H₅O₄P·2Na

Color and Shape: White To Off-White Solid

Molecular weight: 136.04 2*22.99

Ref: 4Z-F-471

Phosphomycin disodium salt

CAS: 26016-99-9

Phosphomycin disodium salt

Formula: C₃H₅O₄P·2Na

Purity: Heavy metals: < 20ppm ph : (Typical Value in Batch COA)

Color and Shape: white to off white powder

Molecular weight: 182.02g/mol

Ref: 54-BIM0107

Fosfomycin sodium

CAS: 26016-99-9

Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria.

Formula: C₃H₅Na₂O₄P

Purity: 99.63%

Color and Shape: Solid

Molecular weight: 182.02

Ref: TM-T8262

Phosphomycin disodium salt

CAS: 26016-99-9

Formula: C₃H₅Na₂O₄P

Purity: ≤ 1.0% (disodium (1,2-dihydroxypropyl)phosphonate)

Color and Shape: White to almost-white powder

Molecular weight: 182.02

Ref: 7W-GA7173

Fosfomycin Disodium Salt

CAS: 26016-99-9

Applications Fosfomycin Disodium Salt is an antibiotic.
References Goto, M., et al.: Antimicrob. Agents Chemother., 20, 393 (1981);

Formula: C₃H₅O₄P·2Na

Color and Shape: Off-White

Molecular weight: 182.02

Ref: TR-F727500

Sodium ((2S,3R)-3-methyloxiran-2-yl)phosphonate

CAS: 26016-99-9

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 182.022

Ref: 10-F242013

Fosfomycin disodium salt, Antibiotic for Culture Media Use Only

CAS: 26016-99-9

Broad-spectrum antibiotic; bacterial cell wall biogenesis inhibitor

Formula: C₃H₅Na₂O₄P

Molecular weight: 182.02 g/mol

Ref: 3D-Q-201134

Fosfomycin disodium

CAS: 26016-99-9

Broad-spectrum antibiotic; bacterial cell wall biogenesis inhibitor

Formula: C₃H₅Na₂O₄P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 182.02 g/mol

Ref: 3D-AF23597

Phosphomycin Disodium Salt (Fosfomycin Disodium Salt) extrapure, 99%

CAS: 26016-99-9

Formula: C₃H₅O₄PNa₂

Purity: min. 99.0%

Color and Shape: White to Off-white, Crystalline powder, Clear, Colourless

Molecular weight: 182.02

Ref: SR-84122

Fosfomycin Disodium

CAS: 26016-99-9

Formula: C₃H₅O₄P(Na)

Molecular weight: 136.04: 2(23.0)

Ref: ST-EA-CP-F6016