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CAS 2604662-64-6

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  • Galectin-3-IN-6
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    Galectin-3-IN-6

    CAS:
    <p>Galectin-3-IN-6 (Compound 12) is an orally active galectin-3 (Gal-3) inhibitor, with an IC50 of 12 nM and a Kd of 13 nM for Gal-3. In a CCl4-induced mouse model of acute liver injury and fibrosis, Galectin-3-IN-6 significantly reduces fibrosis markers collagen-1 and α-smooth muscle actin (αSMA) by 64% and 71%, respectively, demonstrating notable anti-fibrotic activity. Galectin-3-IN-6 is applicable for research in fibrosis-related diseases, cancer, and cardiovascular disorders.</p>
    Formula:C28H29Cl2F3N4O6
    Color and Shape:Solid
    Molecular weight:645.454

    Ref: TM-T206457