As of my last update in October 2023, WM382, with the CAS number 2606990-92-3, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential applications in treating various conditions. While specific characteristics such as its molecular structure, physical properties, and biological activity may not be widely documented in public databases, compounds like WM382 are typically evaluated for their solubility, stability, and reactivity. In research contexts, such substances are often assessed for their pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME), as well as their mechanism of action in biological systems. Additionally, safety profiles, including toxicity and potential side effects, are crucial for any therapeutic candidate. For detailed and specific information, including experimental data and research findings, consulting scientific literature or databases dedicated to chemical substances is recommended.

WM-382 is a PMX inhibitor with antimalarial activity. Oral administration of WM382 cured mice of P. berghei and prevented blood infection from the liver. In addition, WM382 was efficacious against P. falciparum asexual infection in humanized mice and prevented transmission to mosquitoes

WM382

2606990-92-3: As of my last update in October 2023, WM382, with the CAS number 2606990-92-3, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential applications in treating various conditions. While specific characteristics such as its molecular structure, physical properties, and biological activity may not be widely documented in public databases, compounds like WM382 are typically evaluated for their solubility, stability, and reactivity. In research contexts, such substances are often assessed for their pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME), as well as their mechanism of action in biological systems. Additionally, safety profiles, including toxicity and potential side effects, are crucial for any therapeutic candidate. For detailed and specific information, including experimental data and research findings, consulting scientific literature or databases dedicated to chemical substances is recommended.

<p>(R)-4-(2-Amino-4,4-diethyl-6-oxo-5,6-dihydropyrimidin-1(4H)-yl)-N-((S)-2,2-dimethylchroman-4-yl)chromane-6-carboxamide</p>

(R)-4-(2-Amino-4,4-diethyl-6-oxo-5,6-dihydropyrimidin-1(4H)-yl)-N-((S)-2,2-dimethylchroman-4-yl)chromane-6-carboxamide

WM382, a potent dual PMIX/X inhibitor, has IC50s of 1.4 nM/0.03 nM and effective against various malaria stages.

CAS 2606990-92-3

WM382

(R)-4-(2-Amino-4,4-diethyl-6-oxo-5,6-dihydropyrimidin-1(4H)-yl)-N-((S)-2,2-dimethylchroman-4-yl)chromane-6-carboxamide

Ref: 54-OR1074797

WM382

Ref: TM-T73546