CAS 2609-46-3: Amiloride

Description: Amiloride is a potassium-sparing diuretic primarily used in the treatment of hypertension and heart failure. It functions by inhibiting sodium channels in the epithelial cells of the renal tubules, which reduces sodium reabsorption and promotes diuresis while conserving potassium. The chemical formula of amiloride is C6H8ClN5O, and it features a pyrazine ring structure with an amine group that contributes to its pharmacological activity. Amiloride is typically administered orally and is known for its relatively low side effect profile compared to other diuretics, although it can lead to hyperkalemia if not monitored properly. Its solubility in water is moderate, and it is often formulated as a hydrochloride salt to enhance its stability and bioavailability. Additionally, amiloride has been investigated for potential applications beyond diuresis, including its role in treating conditions like cystic fibrosis and certain types of edema. Overall, amiloride is a valuable therapeutic agent in managing fluid balance and blood pressure.

Formula: C₆H₈ClN₇O

InChI: InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)

InChI key: InChIKey=XSDQTOBWRPYKKA-UHFFFAOYSA-N

SMILES: O=C(NC(=N)N)C1=NC(Cl)=C(N=C1N)N

Synonyms:

• (3,5-Diamino-6-chloropyrazinoyl)guanidine
• 2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-
• 3,5-Diamino-N-(aminoiminomethyl)-6-chloro-2-pyrazinecarboxamide
• 3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide
• 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
• Amilorid
• Amilorida
• Amiloride
• Amipramidin
• Guanamprazine
• Hydikal
• Mk 870
• N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide
• Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-
• Pyrazinecarboxamide, N-amidino-3,5-diamino-6-chloro-

Amiloride Hydrochloride

CAS: 2016-88-8 2609-46-3

• Formula: C₆H₈ClN₇O·HCl
• Purity: >98.0%(HPLC)(N)
• Color and Shape: Light yellow to Yellow to Green powder to crystal
• Molecular weight: 266.09

2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-

CAS: 2609-46-3

• Formula: C₆H₈ClN₇O
• Color and Shape: Solid
• Molecular weight: 229.6270

Amiloride

CAS: 2609-46-3

• Formula: C₆H₈ClN₇O
• Molecular weight: 229.63

3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide

CAS: 2609-46-3

Please enquire for more information about 3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide including the price, delivery time and more detailed …

• Formula: C₆H₈ClN₇O
• Purity: Min. 95%
• Molecular weight: 229.63 g/mol