CAS 26098-04-4: Gentamicin C1a

Description: Gentamicin C1a is an aminoglycoside antibiotic derived from the bacterium Micromonospora purpurea. It is primarily used to treat various bacterial infections, particularly those caused by Gram-negative bacteria. Gentamicin C1a exhibits a broad spectrum of antibacterial activity and works by inhibiting protein synthesis in bacteria, leading to cell death. The substance is characterized by its complex structure, which includes multiple amino sugars and a 2-deoxystreptamine core. It is typically administered via injection due to its poor oral bioavailability. Gentamicin C1a is known for its potential nephrotoxicity and ototoxicity, necessitating careful monitoring of kidney function and hearing during treatment. The drug is often used in combination with other antibiotics to enhance its efficacy and reduce the risk of resistance development. Its pharmacokinetics involve rapid distribution in body tissues, with a half-life that can vary based on renal function. Overall, Gentamicin C1a remains a critical option in the arsenal against serious infections, particularly in hospital settings.

Formula: C₁₉H₃₉N₅O₇

InChI: InChI=1S/C19H39N5O7/c1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17/h8-18,24-27H,3-7,20-23H2,1-2H3/t8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-/m0/s1

InChI key: InChIKey=VEGXETMJINRLTH-BOZYPMBZSA-N

SMILES: OC1C(OCC(O)(C)C1NC)OC2C(O)C(OC3OC(CN)CCC3N)C(N)CC2N

Synonyms:

• <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</smallcap>-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-<smallcap>D</span>-erythro-hexopyranosyl-(1→4)]-2-deoxy-
• Geneticin C_1a
• Gentamicin C1a
• Gentamicin C_1a
• Gentamicin C₃
• Gentamycin C_1a
• O-3-Deoxy-4-C-methyl-3-(methylamino)-β-<span class="text-smallcaps">L</smallcap>-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-<smallcap>D</smallcap>-erythro-hexopyranosyl-(1→4)]-2-deoxy-<smallcap>D</span>-streptamine
• Gentamycin C1a
• Gentamicin C3
• O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-D-streptamine
• D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-

D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-

CAS: 26098-04-4

• Formula: C₁₉H₃₉N₅O₇
• Purity: %
• Color and Shape: Solid
• Molecular weight: 449.5423

Gentamicin C1a pentaacetate salt

CAS: 26098-04-4

• Formula: C₂₉H₅₉N₅O₁₇
• Purity: ≥ 95%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 749.8

Gentamicin C1a

CAS: 26098-04-4

• Formula: C₁₉H₃₉N₅O₇
• Molecular weight: 449.55

Gentamicin C1a

CAS: 26098-04-4

Gentamicin C1a, a major component with antibacterial activity, is the precursor to Etimicin.

• Formula: C₁₉H₃₉N₅O₇
• Color and Shape: Liquid
• Molecular weight: 449.54

Gentamicin C1A Deuterated Pentaacetate Salt

CAS: 26098-04-4

• Formula: C₁₉H₃₉N₅O₇·C₁₀H₂₀O₁₀
• Color and Shape: Neat
• Molecular weight: 449.54+(300.26)

Gentamicin C1a Pentaacetate Salt

CAS: 26098-04-4

Stability Hygroscopic Applications Antibacterial. References Holt, H.A., et al.: J. Antimicrob. Chemother., 34, 747 (1994), …

• Formula: C₂₉H₅₉N₅O₁₇
• Color and Shape: Beige
• Molecular weight: 749.8

Gentamicin C1a

CAS: 26098-04-4

Antibacterial agent with inhibitory properties against bacterial growth

• Formula: C₁₉H₃₉N₅O₇
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 449.54 g/mol

Gentamicin C1a pentaacetate

CAS: 26098-04-4

Pentaacetate; Antibacterial agent with inhibitory properties against bacterial growth

• Formula: C₂₉H₅₉N₅O₁₇
• Purity: Min. 95%
• Color and Shape: Off-White Powder
• Molecular weight: 749.8 g/mol