CAS 26098-04-4
:Gentamicin C1a
Description:
Gentamicin C1a is an aminoglycoside antibiotic derived from the bacterium Micromonospora purpurea. It is primarily used to treat various bacterial infections, particularly those caused by Gram-negative bacteria. Gentamicin C1a exhibits a broad spectrum of antibacterial activity and works by inhibiting protein synthesis in bacteria, leading to cell death. The substance is characterized by its complex structure, which includes multiple amino sugars and a 2-deoxystreptamine core. It is typically administered via injection due to its poor oral bioavailability. Gentamicin C1a is known for its potential nephrotoxicity and ototoxicity, necessitating careful monitoring of kidney function and hearing during treatment. The drug is often used in combination with other antibiotics to enhance its efficacy and reduce the risk of resistance development. Its pharmacokinetics involve rapid distribution in body tissues, with a half-life that can vary based on renal function. Overall, Gentamicin C1a remains a critical option in the arsenal against serious infections, particularly in hospital settings.
Formula:C19H39N5O7
InChI:InChI=1/C19H39N5O7/c1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17/h8-18,24-27H,3-7,20-23H2,1-2H3
InChI key:InChIKey=VEGXETMJINRLTH-BOZYPMBZSA-N
SMILES:O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@H](CN)CC[C@H]2N)[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3
Synonyms:- <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</smallcap>-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-<smallcap>D</span>-erythro-hexopyranosyl-(1→4)]-2-deoxy-
- Geneticin C<sub>1a</sub>
- Gentamicin C1a
- Gentamicin C<sub>1a</sub>
- Gentamicin C<sub>3</sub>
- Gentamycin C<sub>1a</sub>
- O-3-Deoxy-4-C-methyl-3-(methylamino)-β-<span class="text-smallcaps">L</smallcap>-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-<smallcap>D</smallcap>-erythro-hexopyranosyl-(1→4)]-2-deoxy-<smallcap>D</span>-streptamine
- Gentamycin C1a
- Gentamicin C3
- O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-D-streptamine
- D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-
- Gentamisin C3
- GentaMycin C1a Acetate
- O-3-Deoxy-4-C-methyl-3-(methylamino)--L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-erythro-hexopyranosyl-(1-4)]-2-deoxy-D-streptamine
- 6-O-(3-Deoxy-4-methyl-3-methylamino-β-L-arabinopyranosyl)-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-2-deoxy-D-streptamine
- Gentamicin C1a Pentaacetate Salt
- GentaMicin D Acetate
- Geneticin C1a
- Gentamicin D
- O-3-Deoxy-4-C-Methyl-3-(MethylaMino)-β-L-arabinopyranosyl-(1-6)-O-[2,6-diaMino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1-4)]-2-deoxy-D-streptaMine Pentaacetate Salt
- 6-O-[3-Deoxy-4-methyl-3-(methylamino)-β-L-arabinopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-2-deoxy-D-streptamine
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Found 10 products.
D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl-(1→4)]-2-deoxy-
CAS:Formula:C19H39N5O7Purity:%Color and Shape:SolidMolecular weight:449.5423(2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4,6-Diamino-3-(((2R,3R,6S)-3-Amino-6-(Aminomethyl)Tetrahydro-2H-Pyran-2-Yl)Oxy)-2-Hydroxycyclohexyl)Oxy)-5-Methyl-4-(Methylamino)Tetrahydro-2H-Pyran-3,5-Diol
CAS:(2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4,6-Diamino-3-(((2R,3R,6S)-3-Amino-6-(Aminomethyl)Tetrahydro-2H-Pyran-2-Yl)Oxy)-2-Hydroxycyclohexyl)Oxy)-5-Methyl-4-(Methylamino)Tetrahydro-2H-Pyran-3,5-DiolPurity:98+%Molecular weight:449.54g/molGentamicin C1a pentaacetate salt
CAS:Formula:C29H59N5O17Purity:≥ 95%Color and Shape:White to off-white crystalline powderMolecular weight:749.8Gentamicin C1a
CAS:Gentamicin C1a, a major component with antibacterial activity, is the precursor to Etimicin.Formula:C19H39N5O7Color and Shape:SolidMolecular weight:449.54Gentamicin C1a Pentaacetate Salt
CAS:<p>Stability Hygroscopic<br>Applications Antibacterial.<br>References Holt, H.A., et al.: J. Antimicrob. Chemother., 34, 747 (1994), Wilschanski, M., et al.: Am. J. Respir. Crit. Care Med., 161, 860 (2000),<br></p>Formula:C29H59N5O17Color and Shape:BeigeMolecular weight:749.8Gentamicin C1a Deuterated Pentaacetate (>90%)
CAS:Controlled ProductFormula:C19H39N5O7·C10H20O10Color and Shape:NeatMolecular weight:449.54+(300.26)Gentamicin C1a pentaacetate
CAS:<p>Gentamicin C1a pentaacetate is an aminoglycoside antibiotic derivative, which is synthesized through the acetylation of the hydroxyl groups in gentamicin C1a. This compound is derived from the fermentation products of Micromonospora species, a genus of actinobacteria. Its mode of action is similar to that of standard aminoglycosides, primarily involving the binding to bacterial 30S ribosomal subunits. This binding interferes with protein synthesis by causing misreading of mRNA, ultimately leading to the inhibition of protein production and bacterial cell death.</p>Formula:C29H59N5O17Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:749.8 g/molGentamicin C1a
CAS:<p>Gentamicin C1a is an aminoglycoside antibiotic, which is a secondary metabolite derived from the bacterium Micromonospora. This antibiotic functions through a mode of action that involves binding to the 30S subunit of bacterial ribosomes. This binding disrupts protein synthesis by causing misreading of the mRNA, ultimately leading to inhibition of bacterial growth and cellular death.</p>Formula:C19H39N5O7Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:449.54 g/mol
