CAS 26117-02-2
:rifamycin L
Description:
Rifamycin L is a member of the rifamycin class of antibiotics, which are derived from the bacterium Amycolatopsis rifamycinica. It is primarily known for its antibacterial properties, particularly against Mycobacterium tuberculosis, the causative agent of tuberculosis. The compound exhibits a complex structure characterized by a naphthalenic core and a series of functional groups that contribute to its biological activity. Rifamycin L functions by inhibiting bacterial RNA synthesis, specifically targeting bacterial RNA polymerase, which is crucial for transcription. This mechanism of action makes it effective in treating various bacterial infections. Additionally, rifamycin derivatives are known for their stability and solubility in organic solvents, which can influence their pharmacokinetics and bioavailability. The compound is typically administered in a clinical setting, and its use may be accompanied by potential side effects, including hepatotoxicity and interactions with other medications. Overall, rifamycin L represents an important tool in the fight against resistant bacterial strains, particularly in the context of tuberculosis treatment.
Formula:C39H49NO14
InChI:InChI=1/C39H49NO14/c1-17-11-10-12-18(2)38(49)40-24-15-26(53-27(43)16-41)28-29(34(24)47)33(46)22(6)36-30(28)37(48)39(8,54-36)51-14-13-25(50-9)19(3)35(52-23(7)42)21(5)32(45)20(4)31(17)44/h10-15,17,19-21,25,31-32,35,41,44-47H,16H2,1-9H3,(H,40,49)/b11-10+,14-13+,18-12+
Synonyms:- Rifamycin, 4-(hydroxyacetate) (9CI)
- Rifamycin 4-hydroxyacetate
- rifamycin L
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