CAS 261506-26-7
:Fulvestrant-3-sulfate
Description:
Fulvestrant-3-sulfate is a chemical compound that serves as a metabolite of fulvestrant, an estrogen receptor antagonist used primarily in the treatment of hormone receptor-positive breast cancer. This compound is characterized by its sulfate group, which influences its solubility and biological activity. Fulvestrant-3-sulfate exhibits a similar mechanism of action to fulvestrant, binding to estrogen receptors and promoting their degradation, thereby inhibiting estrogen-mediated signaling pathways that can lead to tumor growth. The presence of the sulfate moiety may alter its pharmacokinetics and pharmacodynamics compared to its parent compound. In terms of physical properties, fulvestrant-3-sulfate is typically a solid at room temperature and may exhibit specific melting and boiling points, although these can vary based on purity and formulation. Its chemical structure includes multiple functional groups that contribute to its reactivity and interaction with biological systems. Overall, fulvestrant-3-sulfate plays a significant role in the metabolic pathway of fulvestrant and is of interest in pharmacological studies related to cancer treatment.
Formula:C32H47F5O6S2
Synonyms:- Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, 3-(hydrogen sulfate), (7α,17β)- (9CI)
- Fulvestrant-3-sulfate
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