CAS 261506-27-8

Fulvestrant 3-β-D-Glucuronide

Description:

Fulvestrant 3-β-D-Glucuronide is a glucuronide conjugate of fulvestrant, an estrogen receptor antagonist used primarily in the treatment of hormone receptor-positive breast cancer. This compound is characterized by its glucuronidation, a biochemical process that enhances the solubility and excretion of drugs. The presence of the glucuronide moiety typically increases the compound's stability and alters its pharmacokinetic properties compared to its parent drug. Fulvestrant itself is known for its ability to downregulate estrogen receptors, thereby inhibiting estrogen-mediated cellular proliferation. The glucuronide form may exhibit different biological activity, including altered receptor binding affinity and metabolic pathways. Its CAS number, 261506-27-8, uniquely identifies this compound in chemical databases, facilitating research and regulatory processes. Overall, Fulvestrant 3-β-D-Glucuronide represents an important aspect of drug metabolism and pharmacology, particularly in the context of cancer therapeutics.

Formula: C₃₈H₅₅F₅O₉S

Synonyms:

• (7α,17β)-17-Hydroxy-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-3-yl β-D-Glucopyranosiduronic Acid
• Fulvestrant-β-D-Glucuronide
• Fulvestrant 3-β-D-Glucuronide
• Fulvestrant-3-Glucuronide Lithium Salt
• β-D-Glucopyranosiduronic acid, (7α,17β)-17-hydroxy-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-3-yl (9CI)

Fulvestrant 3-b-D-glucuronide

CAS: 261506-27-8

Ref: 7W-GC2049

Fulvestrant-3-Glucuronide Lithium Salt

CAS: 261506-27-8

Formula: C₃₈H₅₄F₅O₉S·Li

Color and Shape: White To Off-White Solid

Molecular weight: 781.89 6.94

Ref: 4Z-F-313

Fulvestrant 3-β-D-Glucuronide

Controlled Product

CAS: 261506-27-8

Applications A metabolite of Fulvestrant (F862500).
References Rao, P., et al.: J. Steroid Biochem., 25, 417 (1986), Wakeling, A., et al.: J. Steroid Biochem. Mol. Biol., 43, 173 (1992), DeFriend, D., et al.: Cancer Res., 54, 408 (1994),

Formula: C₃₈H₅₅F₅O₉S

Color and Shape: Off-White To Light Beige

Molecular weight: 782.89

Ref: TR-F862510

Fulvestrant 3-b-D-glucuronide

CAS: 261506-27-8

Fulvestrant 3-b-D-glucuronide is a synthetic hormone that has been modified with the Click chemistry. This modification allows for the attachment of saccharides, such as polysaccharides and oligosaccharides. The modification also provides protection against degradative enzymes, which may be useful in increasing drug stability in vivo. Fulvestrant 3-b-D-glucuronide can be custom synthesized to meet your requirements and specifications. It is a high purity product with a CAS number of 261506-27-8 and an appearance of white crystalline powder. Fulvestrant 3-b-D-glucuronide is a complex carbohydrate and sugar that can be used for methylation reactions or glycosylation reactions.

Formula: C₃₈H₅₅F₅O₉S

Purity: Min. 95%

Molecular weight: 782.9 g/mol

Ref: 3D-MF16731

Fulvestrant-3-Glucuronide

CAS: 261506-27-8

Formula: C₃₈H₅₅F₅O₉S

Molecular weight: 782.90

Ref: ST-EA-CP-F24015

Fulvestrant 3-β-D-Glucuronide

CAS: 261506-27-8

Fulvestrant 3-β-D-Glucuronide，Fulvestrant的代谢产物，为葡萄糖醛酸结合物，属于纯抗雌激素类固醇。该化合物可应用于乳腺癌研究领域。

Formula: C₃₈H₅₅F₅O₉S

Color and Shape: Solid

Molecular weight: 782.9

Ref: TM-T82366