Methyl 2-[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazinecarbodithioate, identified by its CAS number 26151-73-5, is a chemical compound characterized by its unique structural features, including a hydrazinecarbodithioate moiety and a cyclohexadiene derivative. This compound typically exhibits properties associated with both hydrazine and dithioate functionalities, which may contribute to its reactivity and potential applications in organic synthesis or as a biological agent. The presence of the cyclohexadiene ring suggests that it may participate in various chemical reactions, including electrophilic aromatic substitution or conjugate addition, due to the electron-rich nature of the double bonds. Additionally, the Z-configuration indicates a specific stereochemistry that can influence its biological activity and interaction with other molecules. Overall, this compound's characteristics make it of interest in fields such as medicinal chemistry and agrochemicals, although specific applications and biological effects would require further investigation.

methyl 2-[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazinecarbodithioate

26151-73-5: Methyl 2-[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazinecarbodithioate, identified by its CAS number 26151-73-5, is a chemical compound characterized by its unique structural features, including a hydrazinecarbodithioate moiety and a cyclohexadiene derivative. This compound typically exhibits properties associated with both hydrazine and dithioate functionalities, which may contribute to its reactivity and potential applications in organic synthesis or as a biological agent. The presence of the cyclohexadiene ring suggests that it may participate in various chemical reactions, including electrophilic aromatic substitution or conjugate addition, due to the electron-rich nature of the double bonds. Additionally, the Z-configuration indicates a specific stereochemistry that can influence its biological activity and interaction with other molecules. Overall, this compound's characteristics make it of interest in fields such as medicinal chemistry and agrochemicals, although specific applications and biological effects would require further investigation.

NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.

CAS 26151-73-5

methyl 2-[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazinecarbodithioate

NDM-1 inhibitor-7

Ref: TM-T205556