CAS 2616-64-0

UDP-glucuronic acid

Description:

UDP-glucuronic acid, or uridine diphosphate glucuronic acid, is a nucleotide sugar that plays a crucial role in the biosynthesis of glycosaminoglycans and the detoxification of various compounds in the body. It is a derivative of uridine diphosphate (UDP) and glucuronic acid, featuring a ribose sugar linked to a uracil base and a glucuronic acid moiety. This compound is involved in the process of glucuronidation, where it serves as a substrate for UDP-glucuronosyltransferases, enzymes that facilitate the conjugation of glucuronic acid to lipophilic substances, enhancing their solubility and excretion. UDP-glucuronic acid is typically found in the cytosol of cells and is essential for the metabolism of drugs, hormones, and other xenobiotics. Its structure includes a high-energy phosphate bond, which is critical for its reactivity and function in biochemical pathways. Overall, UDP-glucuronic acid is vital for maintaining homeostasis and facilitating the elimination of potentially harmful substances from the body.

Formula: C₁₅H₂₂N₂O₁₈P₂

InChI: InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1

InChI key: InChIKey=HDYANYHVCAPMJV-LXQIFKJMSA-N

SMILES: O[C@H]1[C@@H](O[C@H](COP(OP(O[C@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)(=O)O)(=O)O)[C@H]1O)N3C(=O)NC(=O)C=C3

Synonyms:

• α-D-Glucopyranuronic acid, 1→P′-ester with uridine 5′-(trihydrogen diphosphate)
• α-D-Glucopyranuronic acid, ester with uridine 5′-pyrophosphate
• UDP-glucuronic acid
• (2S,3S,4S,5R,6R)-6-{[{[{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid (non-preferred name)
• Glucopyranuronic acid, 1-ester with uridine 5′-pyrophosphate
• Glucopyranuronic acid, 1→5′-ester with uridine 5′-(trihydrogen pyrophosphate), α-D-

Uridine diphosphate glucuronic acid

CAS: 2616-64-0

Uridine diphosphate glucuronic acid

Purity: ≥95%

Molecular weight: 580.29g/mol

Ref: 54-OR97965

UDP-g acid

CAS: 2616-64-0

UDP-g acid

Purity: ≥95%

Molecular weight: 580.29g/mol

Ref: 54-BUP01964

UDP-g acid

CAS: 2616-64-0

UDP-g acid is a sugar used in the production of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid

Formula: C₁₅H₂₂N₂O₁₈P₂

Purity: 99.97% - >99.99%

Color and Shape: Solid

Molecular weight: 580.29

Ref: TM-T8949

UDP-α-D-galacturonic acid

CAS: 2616-64-0

UDP-α-D-galacturonic acid is a biochemical precursor for the synthesis of UDP-glucuronic acid. It is an intermediate in the biosynthesis of glycosaminoglycans, proteoglycans and lipopolysaccharides. This compound has been shown to inhibit the growth of cancer cells by inducing apoptosis in vitro. The presence of this compound may be detected by its ability to act as a substrate for glucuronidation reactions.

Formula: C₁₅H₂₂N₂O₁₈P₂

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 580.29 g/mol

Ref: 3D-MU07657