CAS 26171-23-3

Tolmetin

Description:

Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for the treatment of pain and inflammation associated with conditions such as arthritis. It functions by inhibiting the cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, compounds that mediate inflammation and pain. Tolmetin is characterized by its chemical formula, which includes a carboxylic acid group, contributing to its anti-inflammatory properties. The substance is typically administered orally and is known for its relatively rapid onset of action. Common side effects may include gastrointestinal discomfort, dizziness, and potential allergic reactions. As with other NSAIDs, caution is advised in patients with a history of gastrointestinal issues or cardiovascular disease. Tolmetin's efficacy and safety profile make it a valuable option in managing inflammatory conditions, although it should be used under medical supervision to mitigate risks associated with long-term use.

Formula: C₁₅H₁₅NO₃

InChI: InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18)

InChI key: InChIKey=UPSPUYADGBWSHF-UHFFFAOYSA-N

SMILES: C(=O)(C=1N(C)C(CC(O)=O)=CC1)C2=CC=C(C)C=C2

Synonyms:

• 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid
• 1-Methyl-5-(p-toluoyl)-2-pyrroleacetic acid
• 1-Methyl-5-p-toluoylpyrrole-2-acetic acid
• 1-methyl-5-[(4-methylphenyl)carbonyl]-1H-pyrrole-2-carboxylic acid
• 1H-pyrrole-2-acetic acid, 1-methyl-5-(4-methylbenzoyl)-
• 2-[1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid
• 247-497-2
• 5-[(p-Tolyl)carbonyl]-1-methylpyrrole-2-acetic acid
• McN 2559
• Pyrrole-2-acetic acid, 1-methyl-5-p-toluoyl-
• Tolmetine
• Tolmetino
• [1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid
• sodium [1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetate

2-{1-methyl-5-[(4-methylphenyl)carbonyl]-1H-pyrrol-2-yl}acetic acid

CAS: 26171-23-3

Formula: C₁₅H₁₅NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 257.2845

Ref: IN-DA002RZ0

Tolmetin

CAS: 26171-23-3

Tolmetin

Purity: ≥98%

Molecular weight: 257.28g/mol

Ref: 54-BUP14977

Tolmetin

CAS: 26171-23-3

Tolmetin

Purity: 98%

Molecular weight: 257.29g/mol

Ref: 54-OR1026840

Tolmetin

CAS: 26171-23-3

Formula: C₁₅H₁₅NO₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 257.29

Ref: 3B-T4087

Tolmetin

Controlled Product

CAS: 26171-23-3

Formula: C₁₅H₁₅NO₃

Color and Shape: Neat

Molecular weight: 257.28

Ref: 04-C17591600

Tolmetin

CAS: 26171-23-3

Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.

Formula: C₁₅H₁₅NO₃

Purity: 99.74% - >99.99%

Color and Shape: Off-White Crystalline Power

Molecular weight: 257.28

Ref: TM-T2550

Tolmetine

Controlled Product

CAS: 26171-23-3

Applications 1-Methyl-5-p-toluoylpyrrole-2-acetic acid (cas# 26171-23-3) is a useful research chemical.

Formula: C₁₅H₁₅NO₃

Color and Shape: Neat

Molecular weight: 257.28

Ref: TR-M332943

2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid

CAS: 26171-23-3

2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid is a nonsteroidal antiinflammatory drug that belongs to the group of drugs called arylpropionic acids. The drug is used to relieve inflammation and pain. 2-(1-Methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetic acid has been shown in vitro assays to be toxic to epidermal cells and inhibit the production of inflammatory mediators such as prostaglandins and leukotrienes. The drug also inhibits the production of proinflammatory cytokines such as IL6, IL8, and TNFα by activated human monocytes in vitro. It has been shown to have antiinflammatory activity in experimental models for arthritis, colitis, and asthma.

Formula: C₁₅H₁₅NO₃

Purity: Min. 95%

Molecular weight: 257.28 g/mol

Ref: 3D-FM140506