CAS 26189-59-3

1-Chloro-N,N-2-trimethylpropenylamine

Description:

1-Chloro-N,N-2-trimethylpropenylamine, identified by its CAS number 26189-59-3, is an organic compound characterized by the presence of a chloro group and an amine functional group. This compound features a propenyl chain, which contributes to its reactivity and potential applications in organic synthesis. The presence of the trimethyl groups indicates steric hindrance, which can influence the compound's reactivity and interactions with other molecules. Typically, compounds like this may exhibit properties such as being a colorless to pale yellow liquid, with a distinctive odor. They are often soluble in organic solvents but may have limited solubility in water due to their hydrophobic characteristics. The chloro group can serve as a leaving group in nucleophilic substitution reactions, making this compound useful in various chemical syntheses. Additionally, the amine functionality may allow for hydrogen bonding, affecting its physical properties and reactivity. Safety precautions should be taken when handling this compound, as it may pose health risks due to its reactive nature.

Formula: C₆H₁₂ClN

InChI: InChI=1/C6H12ClN/c1-5(2)6(7)8(3)4/h1-4H3

InChI key: InChIKey=GQIRIWDEZSKOCN-UHFFFAOYSA-N

SMILES: C(=C(C)C)(N(C)C)Cl

Synonyms:

• (1-Chloro-2-methylprop-1-en-1-yl)dimethylamine
• (1-Chloro-2-methylpropenyl)dimethylamine
• 1-Chloro-1-(dimethylamino)-2-methylpropene
• 1-Chloro-N,N,2-trimethyl-1-propen-1-amine
• 1-Chloro-N,N,2-trimethylprop-1-en-1-amine
• 1-Chloro-N,N-2-trimethyl-1-propenylamine
• 1-Chloro-N,N-dimethyl-2-methyl-1-propenylamine
• 1-Chloro-N,N-dimethyl-2-methylprop-1-en-1-amine
• 1-Propen-1-amine, 1-chloro-N,N,2-trimethyl-
• Ghosez's reagent
• N-(1-Chloro-2-methylprop-1-enyl)-N,N-dimethylamine
• Propenylamine, 1-chloro-N,N,2-trimethyl-
• 1-Chloro-N,N-2-trimethylpropenylamine
• TETRAMETHYL-ALPHA-CHLORENAMINE
• 1-Chloro-N,N,2-trimethylpropenylamine ,98%
• 1-Chloro-N,N,2-triMethylpropenylaMine, 98.5+% 5ML
• 1-Chloro-N,N,2-triMethyl-1-propenylaMine 96%
• 1-Chloro-N,N,2-trimethylpropenylamine, 98.5+%

1-Chloro-N,N,2-trimethylprop-1-en-1-amine

CAS: 26189-59-3

1-Chloro-N,N,2-trimethylprop-1-en-1-amine

Formula: C₆H₁₂ClN

Purity: 96%

Color and Shape: clear. colourless liquid

Molecular weight: 133.62g/mol

Ref: 54-OR52956

1-Chloro-N,N,2-trimethylpropenylamine

CAS: 26189-59-3

1-Chloro-N,N,2-trimethylpropenylamine is an organic solvent with a reactive allyl group. It is used in assays to detect the presence of azobenzene. The proton transport properties of this substance have been studied by intramolecular hydrogen transfer and chloride ion exchange. The nature of the allyl group has been determined by NMR spectroscopy and postulated to be a phosphorus oxychloride derivative.

Formula: C₆H₁₂ClN

Purity: Min. 96 Area-%

Color and Shape: Colorless Clear Liquid

Molecular weight: 133.62 g/mol

Ref: 3D-FC145523

1-Chloro-N,N-2-trimethylpropenylamine (>90%)

Controlled Product

CAS: 26189-59-3

Stability Unstable in solution. Small amounts of precipitate should have no effect on use.
Applications 1-Chloro-N,N-2-trimethylpropenylamine acts as a reagent in the synthesis and antitumor activity of (-)-bassianolide in human cancer cells through cell cycle arrest. Enantioselective total synthesis of nannocystins A and A0 as elongation factor 1 inhibitors. Total synthesis of (-)-caprazamycin A with antibacterial activity against Mycobacterium tuberculosis (TB) via diastereoselective aldol reaction.
References Mun, B., et al.: Bioorg. Chem., 69, 64 (2016); Huang, J., et al.: Org. Lett., 18, 4702 (2016); Nakamura, H., et al.: Angew. Chem., Int. Ed., 54, 3136 (2015)

Formula: C₆H₁₂ClN

Purity: >90%

Color and Shape: Neat

Molecular weight: 133.62

Ref: TR-C349260