CAS 2620-62-4

N6-Dimethyladenosine

Description:

N6-Dimethyladenosine is a modified nucleoside derived from adenosine, characterized by the presence of two methyl groups attached to the nitrogen atom at the sixth position of the adenine base. This modification plays a significant role in various biological processes, particularly in RNA metabolism and regulation. N6-Dimethyladenosine is known to influence gene expression and is involved in the regulation of mRNA stability and translation. It is commonly found in eukaryotic cells and is a key component of certain RNA species, including tRNA and rRNA. The presence of this modification can affect the structure and function of RNA, impacting cellular processes such as splicing and translation efficiency. Additionally, N6-Dimethyladenosine has been studied for its potential implications in various diseases, including cancer, where altered methylation patterns can affect gene expression profiles. Its chemical structure and properties make it a subject of interest in both biochemistry and molecular biology research.

Formula: C₁₂H₁₇N₅O₄

InChI: InChI=1S/C12H17N5O4/c1-16(2)10-7-11(14-4-13-10)17(5-15-7)12-9(20)8(19)6(3-18)21-12/h4-6,8-9,12,18-20H,3H2,1-2H3/t6-,8-,9-,12-/m1/s1

InChI key: InChIKey=WVGPGNPCZPYCLK-WOUKDFQISA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N(C)C)N=CN3)O[C@H](CO)[C@H]1O

Synonyms:

• (2xi)-N,N-dimethyladenosine
• 6-(Dimethylamino)purine ribonucleoside
• 6-(Dimethylamino)purine riboside
• 6-Dimethylamino-9-(β-<span class="text-smallcaps">D</span>-ribofuranosyl)purine
• 6-Dimethylaminopurine <span class="text-smallcaps">D</span>-riboside
• 6-Dimethylaminopurine-9-riboside
• Adenosine, N,N-dimethyl-
• N,N-dimethyl-9-pentofuranosyl-9H-purin-6-amine
• N,N-dimethyladenosine
• N⁶,N⁶-Dimethyladenosine
• N⁶-Dimethyladenosine

N6,N6-DIMETHYLADENOSINE

CAS: 2620-62-4

Formula: C₁₂H₁₇N₅O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 295.2945

Ref: IN-DA00BDAF

6-Dimethylamino-9-(b-D-ribofuranosyl)purine

CAS: 2620-62-4

Formula: C₁₂H₁₇N₅O₄

Purity: ≥ 98%

Color and Shape: White to off-white crystalline powder

Molecular weight: 295.30

Ref: 7W-GN8450

N6,N6-Dimethyladenosine

CAS: 2620-62-4

N6,N6-Dimethyladenosine

Purity: ≥98%

Molecular weight: 295.29g/mol

Ref: 54-BUP11740

N6,N6-Dimethyladenosine

CAS: 2620-62-4

N6,N6-Dimethyladenosine

Purity: 99%

Color and Shape: Solid

Molecular weight: 295.29g/mol

Ref: 54-OR928523

N6,N6-Dimethyladenosine

CAS: 2620-62-4

N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.

Formula: C₁₂H₁₇N₅O₄

Purity: 98.79%

Color and Shape: White Powder

Molecular weight: 295.29

Ref: TM-T19464

6-Dimethylaminopurine-9-riboside

Controlled Product

CAS: 2620-62-4

Applications 6-Dimethylaminopurine-9-riboside (cas# 2620-62-4) is a compound useful in organic synthesis.
References Elion, G.B., et al.: JACS, 74, 411-414 (1952), Kelley, J.L., et al.: J. Med. Chem., 32, 1020-1024 (1989)

Formula: C₁₂H₁₇N₅O₄

Color and Shape: White Solid

Molecular weight: 295.29

Ref: TR-D461975

6-Dimethylamino-9-(b-D-ribofuranosyl)purine

CAS: 2620-62-4

6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.

Formula: C₁₂H₁₇N₅O₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 295.3 g/mol

Ref: 3D-ND04708